Director of pediatric neuro-oncology, Associate professor of pediatrics at the University of South Florida
Johns Hopkins All Children’s Hospital
Dr. Stapleton is the director of pediatric neuro-oncology at Johns Hopkins All Children’s Hospital. Dr. Stapleton joined the hospital in 2007 and is double-board certified by the American Board of Pediatrics in general pediatrics and pediatric hematology/oncology. She has formal training in pediatric neuro-oncology.
Dr. Stapleton is on the Pediatric Palliative Care Team at Johns Hopkins All Children’s and she specializes in symptom control and end of life care. She has been awarded numerous grants for phase I studies for patients with brain and spinal cord tumors as well as clinical research in pediatric palliative care. Dr. Stapleton’s research experience includes investigator-initiated and multi-center research projects.
Johns Hopkins Medicine
Identification of Circulating Noncoding RNAs and Metabolites in Cerebrospinal Fluid(CSF) in Medulloblastoma Patients
Medulloblastoma is the most common pediatric brain tumor, and yet there is still much to be learned in order to effectively treat this disease. Researchers will utilize cerebrospinal fluid samples provided by the Children’s Brain Tumor Network in an effort to identify molecular markers that could lead to improved diagnostics, therapies and outcomes.
Medulloblastomas comprises the vast majority of pediatric embryonal tumors and by definition arise in the posterior fossa, where they constitute approximately 40% of all posterior fossa tumors. Other forms of embryonal tumors each make up 2% or less of all childhood brain tumors.The clinical feature