Exploring the Possible Role of Mutations in MTOR pathway Genes in the Pathogenesis of DNET Tumors

Recent tissue-based research suggests that overactivation of the mTOR pathway, central to the regulation of metabolism, growth, proliferation, and survival, could be a driver in the development of various diseases and malformations in children including DNET tumors. Using samples from the CBTN BioBank, researchers will conduct studies into the hyperactivation of the mTOR pathway and its role in the development of DNETs.