Understanding the effect of mismatch repair deficiency on the alternative lengthening of telomeres
Lead Researcher
Roger Greenberg
Lead Institution
University of Pennsylvania
Status
Active
Details
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specimen
Genetic Susceptibility to Medulloblastoma
Lead Researcher
Maral Adel Fahmideh, PhD
Lead Institution
Baylor College of Medicine
Status
Active
Details
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specimen
Genomic Analysis of Oligodendrogilomas across the pediatrics, adolescents and adults
Lead Researcher
Adam Resnick, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
Details
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specimen
Evaluation of immunosignature profile in medulloblastoma
Lead Researcher
Mateusz Koptyra, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
Details
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data
Development of Preclinical Models of Pediatric Ependymoma
Lead Researcher
Ching Lau, MD, PhD
Lead Institution
Jackson Laboratory for Genomic Medicine
Status
Active
Details
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data
Center for Pediatric Tumor Cell Atlas
Lead Researcher
Kristina Cole, MD, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
Details
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specimen
Mechanisms of medulloblastoma formation
Lead Researcher
Erwin Van Meir, PhD
Lead Institution
UAB - Children's of Alabama
Status
Active
Details
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specimen
Rapid Molecular Central Nervous System Tumor Diagnosis
Lead Researcher
Peter Madsen, MD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
Details
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specimen
Molecular and Spatial Insights into Treatment Failure in Pediatric Low-Grade Gliomas
Lead Researcher
Ana Guerreiro Stücklin, MD, PhD
Lead Institution
University Children’s Hospital Zürich
Status
Active
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specimen
Leveraging Deep Learning to Decipher Single-cell Epigenetic Regulation in Diffuse Midline Glioma and Ependymoma
Lead Researcher
Yang Li, PhD
Lead Institution
Washington University School of Medicine
Status
Active
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specimen
Systems biology integration of single-cell and spatial omics data to dissect tumor and tumor microenvironment interaction map of atypical teratoid rhabdoid tumors.
Lead Researcher
Jiyang Yu, PhD
Lead Institution
St. Jude Children's Research Hospital
Status
Active
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specimen
The Proteomic Landscape of Low-Grade Glioma (LGG)
Lead Researcher
Roger Reddel, MD, BSc (Med), MBBS, FRACP, FAAHMS, FAA
Lead Institution
Children's Medical Research Institute
Status
Active
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specimen
Medulloblastoma subgroups stratification using transcriptome and RNA modification landscape
Lead Researcher
Stacie Stapleton, MD
Lead Institution
Johns Hopkins All Children’s Hospital
Status
Active
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specimen
An immuno-epigenomic approach to identify therapeutic opportunities for Paediatric High-Grade Gliomas
Lead Researcher
Claire Sun
Lead Institution
Hudson Institute of Medical Research
Status
Active
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data
ENPP1 inhibition in models of medulloblastoma
Lead Researcher
Sunil Sharma / Stingray
Lead Institution
The Translational Genomics Research Institute (TGen)
Status
Active
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specimen
Investigating disease mechanism in Adamantinomatous Craniopharyngioma using new cell line models.
Lead Researcher
Todd Hankinson, MD
Lead Institution
Children's Hospital Colorado/ University of Colorado Anschutz Medical Campus
Status
Active
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specimen
Genomic Analysis of Chordomas across the pediatrics, adolescents and adults
Lead Researcher
Adam Resnick, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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specimen
Therapeutic targeting of the blood-brain barrier in pediatric malignant brain tumors
Lead Researcher
Sadhana Jackson, MD
Lead Institution
National Institutes of Health (NIH)
Status
Active
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specimen
Targeting medulloblastoma by regulating RNA binding proteins
Lead Researcher
Robert Schnepp
Lead Institution
Emory University
Status
Active
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specimen
Regional Response to ONC201 in Pediatric High-Grade Glioma
Lead Researcher
Carl Koschmann, MD
Lead Institution
University of Michigan
Status
Active
Details
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specimen
Impeding LIN28 function in ATRT
Lead Researcher
Giselle Saulnier Sholler, MD
Lead Institution
Helen DeVos Children's Hospital
Status
Active
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specimen
Identification of circulating noncoding RNAs and metabolites in cerebrospinal fluid (CSF) in medulloblastoma patients
Lead Researcher
Ranjan Perera, PhD
Lead Institution
Johns Hopkins Medicine
Status
Active
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specimen
Targeting regions of converging synteny in pediatric and canine glioma
Lead Researcher
Roel Verhaak, PhD
Lead Institution
Yale University
Status
Active
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specimen
Investigating the Metabolic Hallmarks of Oligodendroglioma
Lead Researcher
Samuel McBrayer, PhD
Lead Institution
University of Texas Southwestern Medical Center
Status
Active
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specimen
Identifying the cells of origins of brain tumors using somatic mutations
Lead Researcher
Gilad Evrony, MD, PhD
Lead Institution
Hassenfeld Children’s Hospital at NYU Langone
Status
Active
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specimen
Delineating pediatric glioma progression using single-nuclei sequencing
Lead Researcher
Trevor Pugh, PhD, FACMG
Lead Institution
University Health Network
Status
Active
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specimen
Personalized therapy for high-risk ependymoma of childhood
Lead Researcher
Vijay Ramaswamy, MD, PhD, FRCPC
Lead Institution
The Hospital of Sick Children (Sick Kids)
Status
Active
Details
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specimen
Microglial Mosaicism in BRAFV600E Glioma
Lead Researcher
Estibaliz Lopez-Rodrigo, MD
Lead Institution
Memorial Sloan Kettering Cancer Center
Status
Active
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specimen
CBTTC cell lines high throughput drug screening study
Lead Researcher
Adam Resnick, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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specimen
Oncolytic virus to potentiate immune-checkpoint blockade in immunologically cold brain tumors
Lead Researcher
Aaron Diaz, PhD
Lead Institution
UCSF Benioff Children’s Hospital
Status
Active
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specimen
Pediatric brain tumor miRNA profiling for the cohort of Children’s Brain Tumor Tissue Consortium specimens
Lead Researcher
Mateusz Koptyra, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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specimen
Exploring the possible role of mutations in MTOR pathway genes in the pathogenesis of DNET tumors.
Lead Researcher
Anna Maria Buccoliero M.D, PhD
Lead Institution
Meyer Children’s Hospital
Status
Active
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specimen
Disclosing chromatin accessibility in brain tumor cells after treatment by cracking a ‘nucleosomal code’
Lead Researcher
Jakub Mieczkowski, PhD
Lead Institution
Nencki Institute of Experimental Biology Polish Academy of Sciences
Status
Active
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specimen
Molecular Analysis of the Cellular Ecosystem of Childhood Ependymoma
Lead Researcher
Pablo Gonzalez-Camara, PhD
Lead Institution
University of Pennsylvania
Status
Active
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specimen
GPC2 as an immunotherapeutic target in medulloblastoma and other pediatric brain tumors
Lead Researcher
Jessica Foster, MD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
Details
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specimen
Interactions between astrocytes and tumor cells are critical for medulloblastoma growth
Lead Researcher
Zeng-Jie Yang, MD, PhD
Lead Institution
Fox Chase Cancer Center
Status
Active
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specimen
Cracking the Histone Code: Characterizing Pediatric Brain Tumor Epigenetics using Cerebrospinal Fluid
Lead Researcher
Amanda M. Saratsis, MD
Lead Institution
Ann & Robert H. Lurie Children’s Hospital of Chicago
Status
Active
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specimen
Elucidating the somatic epigenetic landscape of pediatric meningioma and schwannoma
Lead Researcher
Sameer Agnihotri, PhD
Lead Institution
UPMC Children’s Hospital of Pittsburgh
Status
Active
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specimen
Molecular and functional characterization of childhood supratentorial ependymoma
Lead Researcher
Vijay Ramaswamy, MD, PhD, FRCPC
Lead Institution
The Hospital of Sick Children (Sick Kids)
Status
Active
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specimen
Germline and somatic determinants of paediatric brain tumor evolution
Lead Researcher
Sorana Morrissy, PhD
Lead Institution
University of Calgary
Status
Active
Details
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specimen
Elucidating the role of driver mutations in pediatric High Grade Glioma
Lead Researcher
Thomas De Raedt, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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specimen
Elucidate potential therapeutic targets in H3.3G34 mutant pHGG cells
Lead Researcher
Zhiguo Zhang, PhD
Lead Institution
Columbia University
Status
Active
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specimen
Defining the role of the histone 3 (H3.3G34R) mutation in the pathogenesis of pediatric high astrocytoma
Lead Researcher
Cynthia Hawkins, MD, PhD
Lead Institution
The Hospital of Sick Children (Sick Kids)
Status
Active
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specimen
Released Tumor DNA in the CSF for the Diagnosis and Monitoring of Pediatric Brain Tumors
Lead Researcher
Chetan Betagowda, MD, PhD
Lead Institution
Johns Hopkins Medicine
Status
Active
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specimen
Using whole genome bisulfite sequencing to identify novel therapeutic targets in DIPG and ATRT
Lead Researcher
Eric Raabe, MD, PhD
Lead Institution
Johns Hopkins Medicine
Status
Active
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specimen
The role of genetic factors in ependymoma susceptibility
Lead Researcher
Maral Adel Fahmideh, PhD
Lead Institution
Baylor College of Medicine
Status
Active
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specimen
Circular RNAs in Medulloblastoma
Lead Researcher
Peter George Zaphiropoulos, PhD
Lead Institution
Karolinska Institutet
Status
Active
Details
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specimen
BGI Validation Cohort
Lead Researcher
Adam Resnick, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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specimen
Choroid Plexus Tumor (CPT) therapies based on patient derived cell culture resources
Lead Researcher
Mark Souweidane, MD
Lead Institution
Weill Cornell Medicine
Status
Active
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specimen
Integrative functional genomics of recurrent childhood medulloblastoma.
Lead Researcher
Javad Nazarian, PhD
Lead Institution
Children’s National Hospital
Status
Active
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specimen
Integrated Genomic Analysis to elucidate the role of PIKC3A and 10q LOH as Unique drivers and cooperating events in pediatric high grade gliomas
Lead Researcher
Ian Pollack, MD
Lead Institution
UPMC Children’s Hospital of Pittsburgh
Status
Active
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specimen
HTG EdgeSeq system evaluation using CBTTC FFPE research specimens.
Lead Researcher
Mateusz Koptyra, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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specimen
Sequencing of CBTTC Biorepository
Lead Researcher
Adam Resnick, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
Details
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specimen
Epigenetic basis of gender differences in pediatric GBM
Lead Researcher
Sheng Li, PhD
Lead Institution
Weill Cornell Medicine
Status
Active
Details
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specimen
Medulloblastoma High Resolution Genomic Data for the CBTTC Repository
Lead Researcher
Tom Curran
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
Details
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specimen
Genomic evaluation of malignant pediatric cortical tumors
Lead Researcher
Sarah Leary, MD
Lead Institution
Seattle Children’s Hospital
Status
Active
Details
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specimen
GPC2 CAR T immunotherapy against pediatric central nervous system tumors
Lead Researcher
Jessica Foster, MD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
Details
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specimen
Identification and functional targeting of alternative splice site usage in pediatric high-grade gliomas
Lead Researcher
Jo Lynne Rokita, PhD
Lead Institution
Children’s National Hospital
Status
Active
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specimen
Multi-modal data integration and functional screening to discover druggable targets in pediatric low-grade glioma
Lead Researcher
Pedro Costa-Pinheiro
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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specimen
Exploration of IDO1 as a therapeutic target in pediatric central nervous system tumors
Lead Researcher
Rishi Lulla, MD, MS
Lead Institution
Ann & Robert H. Lurie Children’s Hospital of Chicago
Status
Active
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specimen
Neurocytoma WGS and RNAseq
Lead Researcher
Adam Resnick, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
Details
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specimen
Target identification and modeling of NF1-associated low-grade glioma
Lead Researcher
Michael Fisher, MD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
Details
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specimen
Targeting Replicative Stress in Pediatric Brain Tumors with ALT
Lead Researcher
Kristina Cole, MD, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
Details
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specimen
Proteogenomic Identification of Structural Variations
Lead Researcher
Brian Rood, MD
Lead Institution
Children’s National Hospital
Status
Active
Details
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specimen
Comprehensive molecular analysis of pediatric thalamic tumors
Lead Researcher
Javad Nazarian, PhD
Lead Institution
Children’s National Hospital
Status
Active
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specimen
Development of the ganglioside GD2 as a biomarker and clinical trial endpoint for childhood cancers
Lead Researcher
Frank Balis, MD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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specimen
Identifying tumor cell vulnerabilities in recurrent/progressive human medulloblastomas by single-cell RNA-seq
Lead Researcher
Ninib Baryawno, PhD
Lead Institution
Karolinska Institutet
Status
Active
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specimen
Evaluating the Efficacy of ZIKV Oncolytic Virus Killing Efficiency on Tumor Cell Lines
Lead Researcher
Youssef Kousa, MS, DO, PhD
Lead Institution
Children’s National Hospital
Status
Active
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specimen
Characterizing ATRT subtype evolution
Lead Researcher
Jo Lynne Rokita, PhD
Lead Institution
Children’s National Hospital
Status
Active
Details
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specimen
Differentiation Induction effects of thyroid hormone on tumor cells from atypical teratoid rhabdoid tumor and diffuse midline gliomas
Lead Researcher
Zeng-Jie Yang, MD, PhD
Lead Institution
Fox Chase Cancer Center
Status
Active
Details
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specimen
Development of neoantigen mRNA vaccines for pediatric brain tumors
Lead Researcher
Jessica Foster, MD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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specimen
Examine GFAP-expressing tumor cells
Lead Researcher
Yanxin Pei
Lead Institution
Children’s National Hospital
Status
Active
Details
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specimen
Secretion of GD2-CD3 BiTEs from B7H3 CAR T-Cells Enhances their Anti-Tumor Activity in Pediatric High-Grade Gliomas
Lead Researcher
Shahab Asgharzadeh, MD
Lead Institution
Children's Hospital Los Angeles
Status
Active
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specimen
Antibody-Drug Conjugate for Pediatric Gliomas
Lead Researcher
Neel Pasricha
Lead Institution
"University of California, San Francisco "
Status
Active
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specimen
Development of Blood Plasma cfDNA Assay to Detect the Alternative Lengthening of Telomeres (ALT) Phenotype in Pediatric High-Grade Glioma Patients
Lead Researcher
C. Patrick Reynolds, MD, PhD
Lead Institution
Texas Tech University Health Science Center School of Medicine
Status
Active
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specimen
Role of CRK and CRKL in tumor cell migration in pediatric high grade glioma cell lines
Lead Researcher
Taeju Park, PhD
Lead Institution
Children's Mercy Kansas City
Status
Active
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specimen
Developing a Local Delivery System for Group 3 Medulloblastoma
Lead Researcher
Betty Tyler
Lead Institution
Johns Hopkins University
Status
Active
Details
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specimen
New Treatments for Pediatric Brain Tumors
Lead Researcher
Miriam Bornhorst, MD
Lead Institution
Ann & Robert H. Lurie Children’s Hospital of Chicago
Status
Active
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specimen
Validation of tumor splice targets
Lead Researcher
Jo Lynne Rokita, PhD
Lead Institution
Children’s National Hospital
Status
Active
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specimen
Assessing glioma gene expression signatures from patient biofluids
Lead Researcher
John Prensner, MD, PhD
Lead Institution
University of Michigan
Status
Active
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specimen
Overcoming immunotherapy resistance in Group 3 medulloblastoma
Lead Researcher
Jiyang Yu, PhD
Lead Institution
St. Jude Children's Research Hospital
Status
Active
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specimen
Evaluating inhibitors of exosomes secretion as pan-treatment for medulloblastoma
Lead Researcher
Marina Sokolsky, PhD
Lead Institution
UNC Chapel Hill
Status
Active
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specimen
Epitranscriptomic characterization of pediatric central nervous system tumors
Lead Researcher
Monica Pomaville, MD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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specimen
Neurosurgically-applied chemotherapy for childhood brain tumours arising in the posterior fossa using a biodegradable paste
Lead Researcher
Ruman Rahman, PhD
Lead Institution
University of Nottingham
Status
Active
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specimen
Predictive biomarkers of cognitive outcome in children who received radiation therapy
Lead Researcher
Sabine Mueller
Lead Institution
UCSF Benioff Children’s Hospital
Status
Active
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specimen
Molecular and Functional Characterization of Paediatric Solid Tumours
Lead Researcher
Ron Firestein, MD, PhD
Lead Institution
Hudson Institute of Medical Research
Status
Active
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specimen
Targeting neurodevelopmental pathways in pediatric high-grade gliomas
Lead Researcher
Manuel Valiente, DVM / PhD
Lead Institution
Spanish National Cancer Research Centre
Status
Active
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specimen
Proteogenomic characterization of pediatric hematopoietic malignancies
Lead Researcher
Richard Aplenc, MD, PhD, MSCE
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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specimen
Validation of Germline Variants
Lead Researcher
Sharon Diskin, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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specimen
Metabolic and proteomic landscapes of DMG and DHG: Navigating uncharted paths for therapeutic discovery
Lead Researcher
Cynthia Hawkins, MD, PhD
Lead Institution
The Hospital of Sick Children (Sick Kids)
Status
Active
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specimen
Identification of hCMV antigens in pediatric brain tumors
Lead Researcher
Eric Thompson, MD
Lead Institution
University of Chicago
Status
Active
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data
Mechanism of action and efficacy of ONC201 and ONC206 in DMG preclinical models
Lead Researcher
Varun Vijay Prabhu, BPharm, MS, PhD
Lead Institution
Chimerix
Status
Active
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Generation of a Tissue Micro Array (TMA) from pediatric brain tumor patients
Lead Researcher
Javad Nazarian, PhD
Lead Institution
Children’s National Hospital
Status
Active
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specimen
T cell Receptor Therapies for pediatric High-Grade Gliomas
Lead Researcher
Anthony Wang, MD
Lead Institution
Ronald Regan UCLA Medical Center
Status
Active
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specimen
Drug development for pediatric HGG
Lead Researcher
Michalina Janiszewska, PhD
Lead Institution
The Wertheim UF Scripps Institute
Status
Active
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specimen
Understanding molecular and cellular mechanisms and identifying drug targets in human cancers
Lead Researcher
Rasika Samarasinghe, PhD
Lead Institution
Deakin University
Status
Active
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specimen
Targeting Cell Surface ALK
Lead Researcher
Yael Mosse, MD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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specimen
Investigating somatic mutations in the normal tissues of neurofibromatosis type 1
Lead Researcher
Sam Behjati, BA, BMBCh, PhD, MRCPCH
Lead Institution
Wellcome Sanger Institute
Status
Active
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specimen
Proteomics X01
Lead Researcher
Brian Rood, MD
Lead Institution
Children’s National Hospital
Status
Active
Details
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specimen
Establishment of Liquid Biopsy Platforms from longitudinal medulloblastoma patients
Lead Researcher
Javad Nazarian, PhD
Lead Institution
Children’s National Hospital
Status
Active
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specimen
Evaluating immune biomarkers overlapping in tumor and CSF in pediatric brain tumors
Lead Researcher
Robyn Gartrell, MD, MS
Lead Institution
Columbia University
Status
Active
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specimen
Novel organoid model generation for transformed gliomas in patients with NF1
Lead Researcher
Javad Nazarian, PhD
Lead Institution
Children’s National Hospital
Status
Active
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specimen
CD47 Checkpoint Blockade to treat Choroid Plexus Carcinoma
Lead Researcher
Samuel Cheshier, M.D.,Ph.D.
Lead Institution
Huntsman Cancer Institute
Status
Active
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specimen
Striking brain tumor metabolic vulnerabilities through identification of synthetic lethal pairs
Lead Researcher
Elena Mariotto, PhD
Lead Institution
"University of Padova, Italy"
Status
Active
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specimen
Analyzing circulating tumor DNA in childhood ependymoma CSF
Lead Researcher
Amy A Smith, MD
Lead Institution
Orlando Health Arnold Palmer Hospital for Children
Status
Active
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specimen
Tumor Chemo-Sensitivity Assays for therapy and Targeting Cancer Stem-Like Cell in Patients Affected by high grade glioma
Lead Researcher
Anna Maria Buccoliero M.D, PhD
Lead Institution
Meyer Children’s Hospital
Status
Active
Details
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specimen
Targeting Glioma Oncoproteins with Peptide Centric CAR T Cells
Lead Researcher
Thomas De Raedt, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
Details
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specimen
Proteomic Analysis of Pediatric Craniopharyngiomas
Lead Researcher
Brian Rood, MD
Lead Institution
Children’s National Hospital
Status
Active
Details
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specimen
Identification of Novel therapeutics for choroid plexus carcinoma
Lead Researcher
Mark Souweidane, MD
Lead Institution
Weill Cornell Medicine
Status
Active
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specimen
High-trhoughput drug screening of adamantinomatous craniopharyngioma primary cell lines
Lead Researcher
Jeffrey Greenfield, MD, PhD
Lead Institution
Weill Cornell Medicine
Status
Active
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specimen
Identifying Neuro-Glycoproteome Disruption in Congenital Disorders of Glycosylation
Lead Researcher
Andrew Edmondson, MD, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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specimen
Pediatric Brain Tumor Classification Using Transcriptional Profiles from Low-Cost Nanopore mRNA Sequencing
Lead Researcher
David Kram, MD, MCR
Lead Institution
Wake Forest Baptist Health
Status
Active
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specimen
Assessing Activity of Agents Targeting ALT Cancers in Pediatric Brain Tumor Cell Lines
Lead Researcher
Charles Patrick Reynolds, MD, PhD
Lead Institution
Texas Tech University Health Science Center School of Medicine
Status
Active
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specimen
Mitochondria and Cancer Connections
Lead Researcher
Marni Falk, MD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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specimen
Lipid nanoparticles for the treatment of neurofibromatosis type 2
Lead Researcher
Michael Mitchell, PhD
Lead Institution
University of Pennsylvania
Status
Active
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specimen
Novel Polyvinyl-alcohol microsphere for Everolimus delivery for Subependymal Giant Cell Astrocytoma
Lead Researcher
Lynn Louis, PhD
Lead Institution
Technological University of the Shannon
Status
Active
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specimen
Role of the Immunosuppressive Tumor Microenvironment in Therapeutic Resistance in Pediatric CNS Cancers
Lead Researcher
Kavitha Yaddanapudi, PhD
Lead Institution
University of Louisville School of Medicine
Status
Active
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specimen
CBTN PBTA X01 Data Generation Project
Lead Researcher
Adam Resnick, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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specimen
Profiling the amino acid transporter landscape to inform fluorescent dye development for improved surgical outcome of image-guided intervention in adolescent and young adult glioma patients
Lead Researcher
Stefan Harmsen, PhD
Lead Institution
University of Pennsylvania
Status
Active
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specimen
Drivers of recurrence in PFA ependymoma
Lead Researcher
Vijay Ramaswamy, MD, PhD, FRCPC
Lead Institution
The Hospital of Sick Children (Sick Kids)
Status
Active
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specimen
The role of non-coding RNA in development of pediatric brain tumors
Lead Researcher
Ruty Shai, PhD
Lead Institution
Sheba Medical Center
Status
Active
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specimen
Pharmaco-proteogenomic profiling of pediatric high-grade gliomas
Lead Researcher
Matthew Dun, PhD
Lead Institution
University of New Castle
Status
Active
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specimen
Optical Genome Mapping for the discover of novel structural variants in pediatric brain tumors
Lead Researcher
Miriam Bornhorst, MD
Lead Institution
Children’s National Hospital
Status
Active
Details
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specimen
Establishing a thalamic glioma model
Lead Researcher
Mark Souweidane, MD
Lead Institution
Weill Cornell Medicine
Status
Active
Details
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specimen
Novel platforms for developing therapies for transformed gliomas in patients with NF1
Lead Researcher
Javad Nazarian, PhD
Lead Institution
Children’s National Hospital
Status
Active
Details
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specimen
Evaluating NF2 and Other Tumor Disease Mechanisms
Lead Researcher
Kathrin Meyer, PhD
Lead Institution
Nationwide Children's Hospital
Status
Active
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specimen
Development of CAR-T Cell Therapy for Atypical Teratoid/Rhabdoid Tumors
Lead Researcher
Peter Madsen, MD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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specimen
CBTN and Count Me In, Pediatric Brain Tumor Molecular Characterization Initiative for retrospective subjects enrolled in CBTN
Lead Researcher
Diane Diehl, PhD
Lead Institution
Broad Institute
Status
Active
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specimen
Characterizing the blood brain pediatric brain tumors
Lead Researcher
Mark Souweidane, MD
Lead Institution
Weill Cornell Medicine
Status
Active
Details
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data
Project Hope, High-Grade Glioma-Omics in Pediatric and AYA
Lead Researcher
Adam Resnick, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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Clinical and molecular characterization of rare and newly defined brain tumor entities Including CNS sarcomas, BCOR altered tumors, astroblastomas/MN-1 altered tumors. PLAG1 altered tumors and histologically ambiguous/unclassifiable brain tumors
Lead Researcher
Adriana Fonseca, MD
Lead Institution
Children’s National Hospital
Status
Active
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Development of Cancer Immunoprevention in a High-Risk Population of CMMRD: Characterization of Frameshift Neoantigens in Mismatch Repair Deficient Individuals
Lead Researcher
Yurong Song, PhD
Lead Institution
Frederick National Laboratory for Cancer Research
Status
Active
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Advancing DMG Drug Discovery with an Organoid-Based Toolkit
Lead Researcher
Zhaohui Wang, PhD
Lead Institution
Terasaki Institute for Biomedical Innovation
Status
Active
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Profiling non-canonical open reading frames in pediatric brain cancer
Lead Researcher
John Prensner, MD, PhD
Lead Institution
University of Michigan
Status
Active
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The Role of Histone Chaperones in H3.3K27M-altered Pediatric Diffuse Midline Glioma
Lead Researcher
Angela Liou, MD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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EXPRESSION OF EAAT2 IN DYSEMBRYOPLASTIC NEUROEPITHELIAL TUMORS (DNT) AND IN ANGIOCENTRIC GLIOMA. ITS POSSIBLE ROLE IN THE PATHOGENESIS OF THE EPILEPSY
Lead Researcher
Anna Maria Buccoliero M.D, PhD
Lead Institution
Meyer Children’s Hospital
Status
Active
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Methylation Profiling of Pediatric Brain Tumors
Lead Researcher
Brian Rood, MD
Lead Institution
Children’s National Hospital
Status
Active
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iPC EU Horizon 2020 – Individualized Paediatric Cure: Cloud-based virtual-patient models for precision paediatric oncology
Lead Researcher
Dejan Stepec, MS
Lead Institution
XLAB d.o.o.
Status
Active
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specimen
Use of ependymoma cell lines to test for new therapeutic vulnerabilities
Lead Researcher
Marcel Kool, PhD
Lead Institution
Hopp Children's Cancer Center Heidelberg
Status
Active
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specimen
Oncogene-Induced Senescence in RTK-fused Infant High Grade Gliomas
Lead Researcher
David Kram, MD, MCR
Lead Institution
Wake Forest Baptist Health
Status
Active
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specimen
Investigating the tumorigenesis mechanisms and vulnerabilities of pediatric high-grade gliomas with H3G34R/V
Lead Researcher
Yang Shi, PhD
Lead Institution
Boston Children's Hospital/Ludwig Institute for Cancer Research-University of Oxford
Status
Active
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MET alterations in DMGs
Lead Researcher
Payal Jain, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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Elucidating Heterogeneity of Resistance Across Molecular Subgroups of Pediatric Ependymomas to Inform Future Therapeutics
Lead Researcher
Jeffrey Greenfield, MD, PhD
Lead Institution
Weill Cornell Medicine
Status
Active
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specimen
RP58 and SMARCB1 in AT/RT pathogenesis
Lead Researcher
Nadia Dahmane, PhD
Lead Institution
Weill Cornell Medicine
Status
Active
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specimen
Evaluation of drug vulnerability of NF2 tumor models
Lead Researcher
Joseph Kissil, PhD
Lead Institution
The Wertheim UF Scripps Institute
Status
Active
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specimen
Pre-clinical Studies for NF2 Schwannomas
Lead Researcher
Cristina Fernandez-Valle, PhD
Lead Institution
University of Central Florida
Status
Active
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specimen
Elucidating the ETMR Microenvironment using Next Generation Imaging and Multi-omics Technologies
Lead Researcher
Claire Carter, PhD
Lead Institution
Hackensack Meridian Health Network
Status
Active
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From Data to Treatment: AI-Driven Identification of Molecular Targets and Bio-Inspired Therapeutics for Pediatric Glioma
Lead Researcher
Coralie Ebert
Lead Institution
MeNow Ltd
Status
Active
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Bayer NTRK Fusion Project
Lead Researcher
Rohan Pathmanathan
Lead Institution
Bayer Aktiengesellschaft
Status
Active
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Analysis of outcomes in recently treated subjects with DIPG
Lead Researcher
Joan Robbins, PhD
Lead Institution
DNAtrix
Status
Active
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Multi-Tensor Decompositions for Personalized Pediatric Glioma Diagnostics and Prognostics
Lead Researcher
Sri Priya Ponnapalli, PhD
Lead Institution
"Eigengene, Inc"
Status
Active
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Integrative analysis of childhood cancers
Lead Researcher
Charles Vaske, PhD
Lead Institution
NantOmics
Status
Active
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Determining Prognostic Factors and Genetic Markers that Impact Survival in Recurrent Pediatric Medulloblastoma
Lead Researcher
Chetan Betagowda, MD, PhD
Lead Institution
Johns Hopkins Medicine
Status
Active
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Sex-specific gene expression signatures in pediatric brain tumors
Lead Researcher
Josh Rubin, M.D., Ph.D.
Lead Institution
Washington University School of Medicine
Status
Active
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Genetic architecture of molecular phenotypes in pediatric brain cancers
Lead Researcher
Sebastian Waszak, PhD
Lead Institution
UCSF Benioff Children’s Hospital
Status
Active
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Artificial Intelligence for Pediatric Brain Tumor Detection and Prediction of Disease Progression
Lead Researcher
Patrick Hales, PhD
Lead Institution
University College London
Status
Active
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Investigating the immune response in pediatric glioma subsets
Lead Researcher
Joanna Phillips, MD, PhD
Lead Institution
UCSF Benioff Children’s Hospital
Status
Active
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Detecting driver mutations of central nervous system germ cell tumors
Lead Researcher
Jiguang Wang, PhD
Lead Institution
Hong Kong University of Science and Technology (HKUST)
Status
Active
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Aberrant splicing candidates as potential neoantigen expression in HGG
Lead Researcher
Patrick Pirrotte, PhD
Lead Institution
The Translational Genomics Research Institute (TGen)
Status
Active
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Searching for Differences in Molecular Profile of Pediatric Gliomas
Lead Researcher
Nikolay Ivanov, MD, MS
Lead Institution
Weill Cornell Medicine
Status
Active
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Structural Variants in Human and Canine Cancer datasets
Lead Researcher
Charles Lee, Ph.D., D.Sc., FACMG, FRSC
Lead Institution
The Jackson Laboratory
Status
Active
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Targeting Master Regulator Dependencies in Diffuse Intrinsic Pontine Glioma (DIPG)
Lead Researcher
Jovana Pavisic, MD
Lead Institution
Memorial Sloan Kettering Cancer Center
Status
Active
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Precision Imaging of Pediatric High-grade Gliomas with Quantitative Diffusion Weighted Imaging and Texture Analysis to Identify Imaging Biomarkers That Predict Tumor Genetics and Patient Outcomes
Lead Researcher
Mariam Aboian, MD, PhD
Lead Institution
Yale University
Status
Active
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High dimensional protein characterization of tumor tissues and relevance to outcomes in immunotherapy clinical trials
Lead Researcher
Kristina Cole, MD, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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Defining the role of the histone 3 (H3.3G34R) mutation in the pathogenesis of pediatric high grade astrocytoma
Lead Researcher
Cynthia Hawkins, MD, PhD
Lead Institution
The Hospital of Sick Children (Sick Kids)
Status
Active
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Proteomic Analysis of CBTTC Cell Lines (Procan)
Lead Researcher
Roger Reddel, MD, BSc (Med), MBBS, FRACP, FAAHMS, FAA
Lead Institution
Children's Medical Research Institute
Status
Active
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Defining Molecular Neighborhoods for Pediatric HGG
Lead Researcher
Kenneth Cohen, MD, MBA
Lead Institution
Johns Hopkins All Children’s Hospital
Status
Active
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Stand Up 2 Cancer
Lead Researcher
Mi-Youn Brusniak PhD, PMP
Lead Institution
Fred Hutchinson Cancer Research Center
Status
Active
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Comparison of fusion calling platforms in pediatric DIPG and high‐grade glioma
Lead Researcher
Carl Koschmann, MD
Lead Institution
University of Michigan
Status
Active
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Developing Summative Measures of Paediatric Cancer Risk
Lead Researcher
Mark Cowley, BSc, PhD
Lead Institution
"Children's Cancer Institute (Sydney, AU)"
Status
Active
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Novel neoantigen detection from complex transcriptomic structures in pediatric Brain Tumors
Lead Researcher
Tamer Ahmed Mansour, MD, PhD
Lead Institution
"University of California, Davis"
Status
Active
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Mitochondrial mutations in pediatric brain cancer
Lead Researcher
Paul Boutros, Ph.D., M.B.A
Lead Institution
"University of California, Los Angeles"
Status
Active
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Splicing analysis in ependymoma
Lead Researcher
Marcel Kool, PhD
Lead Institution
Hopp Children's Cancer Center Heidelberg
Status
Active
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The Role of Mutational Signatures in the Development of Childhood Cancer
Lead Researcher
Michael Scheurer, PhD, MPH, FACE
Lead Institution
Baylor College of Medicine
Status
Active
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Exploring the somatic landscape of adult and paediatric chordoma
Cross-species omics integration to identify oncogenic events in pediatric brain tumors
Lead Researcher
Junmin Peng, PhD
Lead Institution
St. Jude Children's Research Hospital
Status
Active
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BRAIN MATCH
Lead Researcher
Stefan Pfister, MD
Lead Institution
"DKFZ, KiTZ (Hopp-Children's Cancer Center, Heidelberg, Germany)"
Status
Active
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Pediatric Pan-Cancer Analysis of Structural Variants
Lead Researcher
Lukas Chavez, PhD
Lead Institution
"University of California, San Diego"
Status
Active
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Genetic Variability Across Major Histocompatibility Complex
Lead Researcher
Tristan J Hayeck, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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A study of outcomes in patients with CNS tumors with BCOR mutations
Lead Researcher
Scott Raskin, DO
Lead Institution
Children’s National Hospital
Status
Active
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A highly usable and fully comprehensive proteogenomic method leveraging the breadth of genetic variation for oncogenic and//or therapeutic novel protein discovery
Lead Researcher
Alex Kentsis, MD PhD
Lead Institution
Memorial Sloan Kettering Cancer Center
Status
Active
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NF HACKATHON
Lead Researcher
Adam Resnick, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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data
Cross disease variant lookup in CBTTC
Lead Researcher
Yiran Guo, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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data
Gene expression correlates of High grade versus low grade Glioma
Lead Researcher
Chad Creighton, PhD
Lead Institution
Baylor College of Medicine
Status
Active
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Landscape of tumor-infiltrating T cell repertoire of pediatric brain tumors
Lead Researcher
Gary Kohanbash, PhD
Lead Institution
UPMC Children’s Hospital of Pittsburgh
Status
Active
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Descriptive “pharmacogenomics analysis” of the CBTTC PBTA cohort
Lead Researcher
Angela Waanders, MD
Lead Institution
Ann & Robert H. Lurie Children’s Hospital of Chicago
Status
Active
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CLINICAL, RADIOLOGIC, AND MOLECULAR CHARACTERISTICS OF ANAPLASTIC PLEOMORPHIC XANTHOASTROCYTOMAS
Lead Researcher
Alberto Bronisco, MD, MS
Lead Institution
UPMC Children’s Hospital of Pittsburgh
Status
Active
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CENTRAL NERVOUS SYSTEM CANCERS IN PATIENTS WITH NON-NEUROFIBROMATOSIS TYPE 1 RASopathies
Lead Researcher
Alberto Bronisco, MD, MS
Lead Institution
UPMC Children’s Hospital of Pittsburgh
Status
Active
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Body Mass Index Trajectories in Craniopharyngioma
Lead Researcher
Shana McCormack, MD, MTR
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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PNOC and SJCRH Collaborative DIPG Radiogenomic Investigation
Lead Researcher
John Lucas, MD, MS
Lead Institution
St. Jude Children's Research Hospital
Status
Active
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Cancer Stemness of Pediatric Tumors
Lead Researcher
Maciej Wiznerowicz, MD, PhD
Lead Institution
International Institute for Molecular Oncology
Status
Active
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Targeting Immunosuppressive Macrophage in Pediatric Brain Tumors
Lead Researcher
Erin Crotty, MD
Lead Institution
Seattle Children’s Hospital
Status
Active
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Detecting Gene Fusions and Subtype Discovery in Pediatric Solid Tumors RNA-Seq using CICERO
Lead Researcher
Scott Newman, PhD
Lead Institution
St. Jude Children's Research Hospital
Status
Active
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Genomics of radiation-induced cavernomas in pediatric tumor patients
Lead Researcher
YouRong Sophie Su MD, DO
Lead Institution
University of Pennsylvania
Status
Active
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Multi-scale model of children with brain tumors
Lead Researcher
Olivier Gevaert, PhD
Lead Institution
Stanford University
Status
Active
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The Australian Bioinformatics Commons Paediatric Cancer Pathfinder Project
Lead Researcher
Mark Cowley, BSc, PhD
Lead Institution
"Children's Cancer Institute (Sydney, AU)"
Status
Active
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Decoding the Dark Matter of the High-Risk Paediatric Cancer Genome
Lead Researcher
Mark Cowley, BSc, PhD
Lead Institution
"Children's Cancer Institute (Sydney, AU)"
Status
Active
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Comparison of CBTTC patient data with molecularly defined stem cell models of pediatric brain tumors
Lead Researcher
Fredrik Swartling, PhD
Lead Institution
"Uppsala University, SWEDEN"
Status
Active
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Discover new therapeutics for DIPG using a systems-based approach:
Lead Researcher
Bin Chen, PhD
Lead Institution
Michigan State University
Status
Active
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Germline determinants of pediatric brain tumors
Lead Researcher
Sorana Morrissy, PhD
Lead Institution
University of Calgary
Status
Active
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Alternative splicing in CBTTC data
Lead Researcher
Shihao Shen, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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Heath Disparities of Pediatric Brain Tumors
Lead Researcher
Xiao-Nan Li, MD, PhD
Lead Institution
Ann & Robert H. Lurie Children’s Hospital of Chicago
Status
Active
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Long non-coding RNA signature of medulloblastoma and AT/RT subtypes
Lead Researcher
Ranjan Perera, PhD
Lead Institution
Johns Hopkins Medicine
Status
Active
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data
Germline variants in pediatric glioblastoma
Lead Researcher
Adam Resnick, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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Deciphering the molecular characteristics of
pediatric meningiomas
Lead Researcher
Nadia Dahmane, PhD
Lead Institution
Weill Cornell Medicine
Status
Active
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data
Genomic correlates with radiation injury
Lead Researcher
Oren Becher, MD
Lead Institution
Northwestern University
Status
Active
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data
Predictive models for transcriptome variations
Lead Researcher
Yoseph Barash, PhD
Lead Institution
University of Pennsylvania
Status
Active
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data
Hudson Monash Paediatric Precision Medicine Program
Lead Researcher
Ron Firestein, MD, PhD
Lead Institution
Hudson Institute of Medical Research
Status
Active
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data
Germline mtDNA variants and somatic mtDNA mutations in Pediatric Brain Tumors
Lead Researcher
Xiaowu Gai, PhD
Lead Institution
Children's Hospital Los Angeles
Status
Active
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data
Pediatric Brain Tumor Classification and Segmentation using Transfer Learning from Adult Datasets
Lead Researcher
Roy Campbell, PhD
Lead Institution
University of Illinois
Status
Active
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Relationships Between Genomic, Imaging, and Histopathologic Characteristics in Pediatric Brain Tumors
Lead Researcher
Benjamin Hartley, MD
Lead Institution
Weill Cornell Medicine
Status
Active
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Comprehensive analysis of structural variants in pediatric brain tumors
Lead Researcher
Lixing Yang, MD, MSc
Lead Institution
University of Chicago
Status
Active
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Molecular characterization of choroid plexus tumors
Lead Researcher
Christian Thomas, MD
Lead Institution
Institute of Neuropathology Münster
Status
Active
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Germline and Somatic Microsatellite Genotypes in Pediatric Brain Tumors
Lead Researcher
Brian Rood, MD
Lead Institution
Children’s National Hospital
Status
Active
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Epigenetic drivers in Medulloblastoma
Lead Researcher
Alexandros Tzatsos, MD, PhD
Lead Institution
George Washington University
Status
Active
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Epigenetic drivers in diffuse intrinsic pontine gliomas (DIPG)
Lead Researcher
Alexandros Tzatsos, MD, PhD
Lead Institution
George Washington University
Status
Active
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Evaluating the landscape of compound heterozygous variants in pediatric diseases
Lead Researcher
Stephen Piccolo, PhD
Lead Institution
Brigham Young University
Status
Active
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Children’s Brain Tumor Tissue Consortium Pediatric Brain Tumor Proteomics Pilot
Lead Researcher
Adam Resnick, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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Treehouse Childhood Cancer Initiative: Identification of therapeutic leads for individual pediatric cancer patients via pan-cancer analysis
Lead Researcher
David Haussler, PhD
Lead Institution
University of California Santa Cruz - Treehouse Childhood Cancer Initiative (UCSC)
Status
Active
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Genetic Polymorphisms and Neurocognitive Outcomes in Pediatric Brain Tumor Survivors
Lead Researcher
Angela Waanders, MD
Lead Institution
Ann & Robert H. Lurie Children’s Hospital of Chicago
Status
Active
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Identification of non-coding drivers from brain tumour genomes
Lead Researcher
Lincoln Stein, MD, PhD
Lead Institution
Ontario Institute for Cancer Research
Status
Active
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data
Fusion Analysis in CBTTC RNAseq data
Lead Researcher
Olivier Elemento, PhD
Lead Institution
Weill Cornell Medicine
Status
Active
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In silico neo-antigen detection in high grade pediatric brain tumors utilizing RNA-seq and WGS
Lead Researcher
Peter Madsen, MD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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Derek Wainright on IDO1 expression with all the CBTTC RNA-Seq data
Lead Researcher
Derek Wainwright, PhD
Lead Institution
Northwestern University
Status
Active
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Spatial evolution and somatic mutations spectrum of Gliomatosis Cerebri
Lead Researcher
Jeffrey Greenfield, MD, PhD
Lead Institution
Weill Cornell Medicine
Status
Active
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Defining the mutational landscape of pediatric brain tumors
Lead Researcher
Sharon Diskin, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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Cooperating mutations in brain tumors of patients with NF1
Lead Researcher
Thomas De Raedt, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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Comparison of Clinical Targeted Next Generation Sequencing (NGS) in FFPE with whole genome sequencing (WGS) of snap frozen pediatric brain tumors
Lead Researcher
Bonnie Cole, MD
Lead Institution
Seattle Children’s Hospital
Status
Active
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Cancer Predisposition in Pediatric Brain Tumors
Lead Researcher
Suzanne McFarland, MD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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Genomic Landscape of Mixed Glial Neuronal Tumors
Lead Researcher
Lea Surrey, MD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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Identifying New Cell Surface Targets for Immunotherapy treatment of Poor Prognosis Pediatric Brain Tumors
Lead Researcher
Misty Jenkins, PhD
Lead Institution
Walter and Eliza Hall of Medical Research
Status
Active
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Immunogenomic landscape of pediatric cancers
Lead Researcher
Trevor Pugh, PhD, FACMG
Lead Institution
University Health Network
Status
Active
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identify novel therapeutic targets and biomarkers in non-coding genome of pediatric cancers
Lead Researcher
Lihua Zou, PhD
Lead Institution
Northwestern University
Status
Active
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Characterizing the Prevalence of ETMR by Molecular Signature
Lead Researcher
Derek Hanson, MD
Lead Institution
Hackensack Meridian Health Network
Status
Active
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data
Detection of cooperative and mutually exclusive genetic alterations in pediatric cancer
Lead Researcher
Patrick Kemmeren, PhD
Lead Institution
Princess Máxima Center for Pediatric Oncology
Status
Active
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Classification of Pediatric Brain Tumor
Lead Researcher
Ajeya S R
Lead Institution
Vidyavardhaka College Of Engineering
Status
Active
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Characterizing Tumor Diffusion in Gliomatosis Cerebri Using Radiology and MRI Data
Lead Researcher
Sabine Mueller, MD, PhD
Lead Institution
UCSF Benioff Children’s Hospital
Status
Active
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data
Long read sequencing for rapid diagnosis of pediatric brain tumors
Lead Researcher
Derek Wong
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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HD-GLIO 2.0
Lead Researcher
Gianluca Brugnara
Lead Institution
Bonn University Hospital (Universitätsklinikum Bonn)
Status
Active
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Image-Based Classification of Pediatric Posterior Fossa Tumors: An End-to-End Solution
Lead Researcher
Asim Bag
Lead Institution
St. Jude Children's Research Hospital
Status
Active
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Clinical Outcomes Following Volumetric Analysis of Extent of Resection in Medulloblastoma
Lead Researcher
Peter Madsen, MD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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Molecular Predictors of e-Radiation Resistance in H3K27M alerted diffuse midline gliomas
Lead Researcher
Sabine Mueller, MD, PhD
Lead Institution
UCSF Benioff Children’s Hospital
Status
Active
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Automated Segmentation and Radiomics Integration for Non-Invasive Genetic and Prognostic Prediction in Pediatric High-Grade Gliomas
Lead Researcher
Kartik Reddy
Lead Institution
Children’s Healthcare of Atlanta
Status
Active
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Identification of medulloblastoma metastases
Lead Researcher
Eric Thompson
Lead Institution
Washington University School of Medicine
Status
Active
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Understanding the role of glioma-associated oligodendroglia in glioma progression
Lead Researcher
Claudia K Petritsch
Lead Institution
Stanford University
Status
Active
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FOXR2 driver events and clinical outcomes in CNS neuroblastoma with FOXR2 activation
Lead Researcher
Jessica Tsai
Lead Institution
Children's Hospital Los Angeles
Status
Active
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Characterizing the landscape of cancer-specific splicing aberrations across pediatric tumors
Lead Researcher
Darwin Kwok
Lead Institution
UCSF Benioff Children’s Hospital
Status
Active
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data
Artificial Intelligence Meets Medulloblastoma: Breaking Barriers in Subgroup Prediction
Lead Researcher
Maysa Al-husseini
Lead Institution
King Hussein Cancer Center
Status
Active
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Quantitative analysis of radiographic images and its application to automated diagnosis to improve healthcare efficiency
Lead Researcher
Akifumi Hagiwara
Lead Institution
Juntendo University
Status
Active
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Multiparametric Magnetic Resonance Imaging and Machine Learning-Based Predicts Prognosis and Treatment Response in Pediatric Medulloblastoma
Using AI for Diagnostic and Prognostic Prediction in Paediatric Brain Cancer
Lead Researcher
Jordan Hansford
Lead Institution
University of Adelaide; Australian Institute of Machine Learning
Status
Active
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Radiogenomics and survival correlation of MRI based biomarker using deep learning
Lead Researcher
Akshaykumar Kamble
Lead Institution
Deep Learning Institute of Radiological Sciences
Status
Active
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Analysis of chromatin pathways as regulators of high grade glioma gene expression patterns
Lead Researcher
Jamie Anastas, PhD
Lead Institution
Boston Children's Hospital
Status
Active
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Personalized Survival Prediction of Glioma via Multi-modal Data
Lead Researcher
Jieqiong Wang
Lead Institution
University of Nebraska Medical Center
Status
Active
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Brain Age as a Biomarker for Survivorship Outcomes in Pediatric Brain Tumor Patients: A Neuroimaging-Based Investigation
Lead Researcher
Sahil Bajaj
Lead Institution
UT MD Anderson Cancer Center
Status
Active
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Radiologic-Molecular Correlation in DMG Recurrence
Lead Researcher
Miriam Bornhorst, MD
Lead Institution
Ann & Robert H. Lurie Children’s Hospital of Chicago
Status
Active
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circRNA atlas of pediatric brain tumors
Lead Researcher
Marc Remke
Lead Institution
Universitäts des Saarlandes
Status
Active
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The role of “adult onset” cancer predisposition genes in pediatric cancer
Lead Researcher
Miriam Bornhorst, MD
Lead Institution
Ann & Robert H. Lurie Children’s Hospital of Chicago
Status
Active
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Design, implementation, and validation of novel multimodal deep learning algorithms for clinical translation of diagnostic and prognostic tools for pediatric brain tumors
Lead Researcher
Farzad Khalvati
Lead Institution
The Hospital of Sick Children (Sick Kids)
Status
Active
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Assessing the importance of reoperation in overall survival in pediatric malignant brain tumors
Lead Researcher
Eric Thompson
Lead Institution
Washington University School of Medicine
Status
Active
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Automated Classification of Pediatric Posterior Fossa Tumors Using Machine Learning and Deep Learning on MRI Data
Lead Researcher
Marianne Schell
Lead Institution
Heidelberg University Hospital
Status
Active
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Integrative Multi-omics Approaches to identify novel biomarker-informed therapeutic targets for childhood cancer.
Lead Researcher
Claire Sun
Lead Institution
Hudson Institute of Medical Research
Status
Active
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Digitizing Pathology: Enhancing Tumor Diagnosis with AI and Whole Slide Imaging
Lead Researcher
Jennifer Cotter
Lead Institution
Children's Hospital Los Angeles
Status
Active
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Deep Learning Based Interpretable Pediatric Brain Tumors Segmentation and Classification
Lead Researcher
Ayse Keles
Lead Institution
"University of Galway, School of Computer Science"
Status
Active
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Advancing radiomic tools for brain tumours: Enriching data sets and developing novel AI approaches
Lead Researcher
John Apps
Lead Institution
University of Birmingham
Status
Active
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data
Role of CRK and CRKL in high grade glioma cell migration
Lead Researcher
Taeju Park, PhD
Lead Institution
Children's Mercy Kansas City
Status
Active
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HG34-mutant gliomas
Lead Researcher
Chetan Betagowda, MD, PhD
Lead Institution
Johns Hopkins Medicine
Status
Active
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Automated Multimodal Data Integration and Analysis for Pediatric Brain Tumor Imaging and Pathology
Lead Researcher
Ariana Familiar, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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lncRNA Regulation of Chromatin Remodeling in Pediatric Brain Tumors
Lead Researcher
Hua-Sheng Chiu
Lead Institution
Texas Children’s Hospital
Status
Active
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data
AI/ML derivation and experimental validation of ATRT biomarkers of survival and response to treatment
Lead Researcher
Jessica Tsai
Lead Institution
Children's Hospital Los Angeles
Status
Active
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data
Evolutionary trajectories of pediatric cancers
Lead Researcher
Giulio Caravagna
Lead Institution
Università degli studi di Trieste
Status
Active
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Prediction of radiotherapy benefit using genomic-adjusted radiation dose in pediatric low grade gliomas and ependymomas
Lead Researcher
Javier Torres-Roca
Lead Institution
Moffitt Cancer Center
Status
Active
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Advancing Pediatric Cancer Diagnosis: Unveiling ecDNA Patterns in FFPE Tissue Images Using Machine Learning
Lead Researcher
Zahra Ahmadi
Lead Institution
Medizinische Hochschule Hannover
Status
Active
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Hypoxia and Immune Infiltration in Medulloblastoma
Lead Researcher
Hideho Okada
Lead Institution
UCSF Benioff Children’s Hospital
Status
Active
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data
DMG genomic signatures as predictors of radiation response
Lead Researcher
Cassie Klein, MD, MAS
Lead Institution
UCSF Benioff Children’s Hospital
Status
Active
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data
Understanding a rare familial cancer syndrome associated with multifocal malignant peripheral nerve sheath tumors
Lead Researcher
David Thomas
Lead Institution
University of New South Wales
Status
Active
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data
None Provided
Lead Researcher
Marco Gallo, PhD
Lead Institution
Texas Children’s Hospital
Status
Active
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data
No Change
Lead Researcher
Marco Gallo, PhD
Lead Institution
University of Calgary
Status
Active
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data
Germline mutations in pediatric brain tumors
Lead Researcher
Marco Gallo, PhD
Lead Institution
Texas Children’s Hospital
Status
Active
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An integrated deep learning model to accurately predicts DNA methylation signatures and tumor types from histopathology in central nervous system tumors
Lead Researcher
Lalchung Nunga
Lead Institution
National Cancer Institute
Status
Active
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Enhancing Clinical Data for CBTN through Automated EHR extraction
Lead Researcher
Allison Heath, PhD, MS, BS
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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data
Genomic and transcriptomic profiling
Lead Researcher
Javad Nazarian, PhD
Lead Institution
Children’s National Hospital
Status
Active
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Novel ADC targets in Pediatric Glioma
Lead Researcher
Florian Muller
Lead Institution
Powder Gate Discovery
Status
Active
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Genetic mutations and Epigenetic data
Lead Researcher
Javad Nazarian, PhD
Lead Institution
Children’s National Hospital
Status
Active
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Exploring Shared and Unique Mechanisms of Focal Amplification in Pediatric and Adult Brain Tumors
Lead Researcher
Hoon Kim, PhD
Lead Institution
Sungkyunkwan University School of Pharmacy
Status
Active
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Record ID 1296
Page 8
Characterization of splicing-derived neoantigens in pediatric brain tumors
Lead Researcher
Darwin Kwok
Lead Institution
UCSF Benioff Children’s Hospital
Status
Active
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Human-centered design of clinical AI to support the diagnosis of pediatric suprasellar tumors
Lead Researcher
Todd Hankinson, MD
Lead Institution
Children's Hospital Colorado/ University of Colorado Anschutz Medical Campus
Status
Active
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CAR Target discovery
Lead Researcher
Jessica Foster, MD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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data
Identification of pediatric DIPG targets and Drug Discovery
Lead Researcher
Antonio Scilimati, PhD
Lead Institution
University of Bari (Italy)
Status
Active
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data
Developing an imaging clinical decision support tool
Lead Researcher
Angela Waanders, MD
Lead Institution
Ann & Robert H. Lurie Children’s Hospital of Chicago
Status
Active
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Federated Cancer Data – Paediatric High Grade Glioma Pathfinder Project
Lead Researcher
Angela Waanders, MD
Lead Institution
Ann & Robert H. Lurie Children’s Hospital of Chicago
Status
Active
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Genetic analysis of recurrent medulloblastoma
Lead Researcher
Hiromichi Suzuki, MD, PhD
Lead Institution
National Cancer Center (Japan)
Status
Active
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Precision Diagnosis of Pediatric Tumors Based on Artificial Intelligence Pathology Analysis
Lead Researcher
Biyue Zhu, PhD
Lead Institution
Children's Hospital of Chongqing Medical University
Status
Active
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Clinical Characteristics and Factors Influencing Outcomes of Diffuse Hemispheric Glioma, H3 G34-mutant: A Multi-Institutional Retrospective Cohort Study
Lead Researcher
Cameron Crowell, MD
Lead Institution
"IWK Health Centre, Dalhousie University"
Status
Active
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Defining the global impact of germline structural variation on the transcriptome of human pediatric brain cancers
Lead Researcher
Chad Creighton, PhD
Lead Institution
Baylor College of Medicine
Status
Active
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data
GDF15 in Pediatric Neuro-Oncology Patients
Lead Researcher
Daniel Runco, MD, MS
Lead Institution
Seattle Children’s Hospital
Status
Active
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data
Pediatric and Young Adult Meningioma
Lead Researcher
Joshua Byers, MD
Lead Institution
UCSF Benioff Children’s Hospital
Status
Active
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data
Analysis of allele specific copy-number profiles in the CBTN HGG HOPE cohort
Lead Researcher
Marcin Cieslik, PhD
Lead Institution
University of Michigan
Status
Active
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data
Neoadjuvant LAG-3 Inhibitor + PD-1 Inhibitor in Children with Recurrent or Progressive High-Grade Glioma and Ependymoma
Lead Researcher
Tom Belle Davidson, MD
Lead Institution
Children's Hospital Los Angeles
Status
Active
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data
Explainable AI prediction model with radiogebomics analysis
Lead Researcher
Daisuke Kawahara, PhD
Lead Institution
Hiroshima University
Status
Active
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data
Classification of central nervous system tumors based on predicting DNA methylation from digital pathology.
Lead Researcher
Kenneth Aldape, MD
Lead Institution
National Cancer Institute
Status
Active
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Finding genetic and imaging biomarkers of tumour subtype and clinical outcome in childhood brain cancer
Lead Researcher
Shraddha Pai, PhD
Lead Institution
Ontario Institute for Cancer Research
Status
Active
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Integrative multi-omics analysis reveals dynamic interaction between brain tumors and the immune system
Lead Researcher
Heejin Cho, PhD
Lead Institution
Kyungpook National University
Status
Active
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Molecular Basis of Pediatric Brain Tumor Morphology
Lead Researcher
Arash Nazeri, MD
Lead Institution
St. Louis Children’s Hospital
Status
Active
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The evolution of alternative splicing in pediatric brain tumor under therapy
Lead Researcher
BaoBao Geng, MS
Lead Institution
Center of Systems Medicine Chinese Academy of Medical Sciences Institute of Systems Medicine
Status
Active
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Correlating molecular profiles of pediatric glioma specimens to multiparametric analysis of MR voxels at biopsy sites
Lead Researcher
Jason G Parker
Lead Institution
Indiana University School of Medicine
Status
Active
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data
Deciphering RNA modifications and functional characterization of RNA modification enzymes in Medulloblastoma
Lead Researcher
Ranjan Perera, PhD
Lead Institution
Johns Hopkins Medicine
Status
Active
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Integrated Imaging and Genomic Characterization of the Immunogenicity of Pediatric Low Grade Gliomas
Lead Researcher
Adam Kraya, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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Deep learning enabled medulloblastoma prognosis and biomarker discovery
Lead Researcher
Yongji Tian, MD
Lead Institution
Beijing Tiantan Hospital Neurosurgery Center
Status
Active
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Predictive Analytics in Pediatric High-Grades Gliomas
Lead Researcher
Angela Waanders, MD
Lead Institution
Ann & Robert H. Lurie Children’s Hospital of Chicago
Status
Active
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Predicting Overall Survival for DMG Tumors Based on pre and post-RT MRI
Lead Researcher
Anahita Fathi Kazerooni, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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Which Pediatric High-Grade Glioma Patients Respond to Double Alkylator Chemotherapy?
Lead Researcher
Adam Green, MD
Lead Institution
University of Colorado
Status
Active
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data
Alternative Splicing Analysis of pHGG
Lead Researcher
Matthew Mouck
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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MHC-1 and Histon mutation
Lead Researcher
Maria Castro, PhD
Lead Institution
University of Michigan
Status
Active
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data
Biology of choroid plexus carcinoma
Lead Researcher
Holly Lindsay, MD, MS
Lead Institution
Texas Children’s Hospital
Status
Active
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data
Medulloblastoma Multi-Omics
Lead Researcher
Paul Northcott, PhD
Lead Institution
St. Jude Children's Research Hospital
Status
Active
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Deciphering the 3D genome of pediatric brain tumors
Lead Researcher
Kathrin Pollard, PhD
Lead Institution
UCSF Benioff Children’s Hospital
Status
Active
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Clinicopathologic analysis of novel IDH-wildtype cerebral and posterior fossa diffuse high-grade gliomas
Lead Researcher
MacLean Nasrallah, MD PhD
Lead Institution
University of Pennsylvania
Status
Active
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Methotrexate Outcomes in Infant Medulloblastoma and ETMR Outcomes
Lead Researcher
Rebecca Ronsley, MD, FRCPC
Lead Institution
Seattle Children’s Hospital
Status
Active
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Creating Methylation Classifier for CNS Tumors
Lead Researcher
Marilyn M. Li, MD, MS
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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An investigation into the role of novel and understudied genes in the initiation and progression of medulloblastoma
Lead Researcher
Roger Abounader, MD, PhD
Lead Institution
University of Virginia
Status
Active
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data
A CBTN case study utilizing network analysis
Lead Researcher
Irene Suilan Zeng, PhD
Lead Institution
"Auckland University of Technology, New Zealand"
Status
Active
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Characterize the immune microenvironment of DMG using single-cell based deconvolution approaches
Lead Researcher
Anne Rios, PhD
Lead Institution
Princess Máxima Center for Pediatric Oncology
Status
Active
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Evaluating immune biomarkers overlapping in tumor and CSF in diffuse midline glioma (DMG)
Lead Researcher
Robyn Gartrell, MD, MS
Lead Institution
Columbia University
Status
Active
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data
Universal Pediatric CNS Tumor Genomic Profiling
Lead Researcher
Adam Kraya, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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data
Optimal validation of DNA-methylation based tumor purity estimation
Lead Researcher
Antonios Papanicolau-Sengos, MD
Lead Institution
National Cancer Institute
Status
Active
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data
OpenPBTA: An Open Pediatric Brain Tumor Atlas
Lead Researcher
Jo Lynne Rokita, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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Self-attention feature pyramid network for multimodal medical image segmentation
Lead Researcher
Nico Loesch, M.Sc.
Lead Institution
University of Technology Sydney (UTS)
Status
Active
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data
Pediatric Brain Tumor Classification
Lead Researcher
Anushka Sharma
Lead Institution
"International Institute of Information Technology, Bhubaneswar (IIIT-BH)"
Status
Active
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The role and regulation of tumor suppressor SETD2 in pediatric high grade glioma
Lead Researcher
Angela Liou, MD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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Spatiotemporal multi-omics analysis of childhood ependymoma
Lead Researcher
Semin Lee, PhD
Lead Institution
Ulsan National Institute of Science and Technology
Status
Active
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data
Exploring microbial signatures in childhood tumors
Lead Researcher
Vicky Yao, PhD
Lead Institution
Rice University
Status
Active
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data
Mathematical modelling of drug delivery in brain tumour using thermosensitive hydrogel
Lead Researcher
Wenbo Zhan, PhD
Lead Institution
University of Aberdeen
Status
Active
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Regulation and Function of Circular RNAs in Atypical Teratoid Rhabdoid Tumor
Lead Researcher
Rui Zhou
Lead Institution
Johns Hopkins University
Status
Active
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data
Posterior Fossa Deep Learning Model Validation
Lead Researcher
Maliha Imami, HBSc
Lead Institution
Johns Hopkins University
Status
Active
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Factors Associated with High Incidence of Pediatric Bran and Central Nervous System Tumors in Kentucky
Lead Researcher
Eric B Durbin, DrPH, MS
Lead Institution
University of Kentucky
Status
Active
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data
BRATS validation study/no public access
Lead Researcher
Anahita Fathi Kazerooni, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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data
Validation of a transcriptomic biomarker of pediatric meningioma outcomes and radiotherapy response
Lead Researcher
David Raleigh, MD, PhD
Lead Institution
"University of California, San Francisco "
Status
Active
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Developing Deep-Learning Approaches for the Automated Segmentation of Pediatric Tumors on Multi-Modal MRI Sequences
Lead Researcher
Ramandeep Kang
Lead Institution
University of Liverpool
Status
Active
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Characterization of pediatric CNS tumors using nanopore sequencing
Lead Researcher
Jeremy Wang, PhD
Lead Institution
UNC Chapel Hill
Status
Active
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data
Characterizing the molecular landscape of pediatric and adult meningiomas
Lead Researcher
Damian Andres Almiron Bonnin, MD, PhD
Lead Institution
Fred Hutchinson Cancer Research Center
Status
Active
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data
Comparing gene expression patterns in high v low grade gliomas to understand drivers of tumor cell invasion.
Lead Researcher
Laura Prolo, MD, PhD
Lead Institution
Lucile Packard Children’s Hospital Stanford
Status
Active
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data
Is KIF20A overexpressed in pediatric high-grade glioma?
Lead Researcher
Morgan Schrock, PhD
Lead Institution
The Ohio State University
Status
Active
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data
Developing Novel Precision Medicine for Glioblastoma
Lead Researcher
Zhi Sheng, PhD
Lead Institution
Fralin Biomedical Research Institute at VTC
Status
Active
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Paediatric Brain Tumour Classification and Segmentation
Lead Researcher
Asad Shahzad
Lead Institution
Forman Christian College
Status
Active
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Genome-wide Sequencing to Identify the Genes Responsible for Enchondromatoses and Related Malignant Tumors
Lead Researcher
Nara Sobreira, MD, PhD
Lead Institution
Johns Hopkins University
Status
Active
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Optimizing radiation for ATRT: Understanding the implications of dose and volume on outcomes
Lead Researcher
Sahaja Acharya, MD
Lead Institution
Johns Hopkins Medicine
Status
Active
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data
Discovering new mutations in pediatric neurocancer
Lead Researcher
Cynthia Hawkins, MD, PhD
Lead Institution
The Hospital of Sick Children (Sick Kids)
Status
Active
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data
MRI-based tracking of cell population dynamics to design personalised adaptive treatment protocols for glioma patients
Lead Researcher
Mohammad Amin Lessan, PhD
Lead Institution
University College London
Status
Active
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data
Semi-automated variant curation algorithm
Lead Researcher
Kitty Lo, PhD
Lead Institution
"Children's Cancer Institute (Sydney, AU)"
Status
Active
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data
Methylation profiling of pediatric CNS tumors to define molecular subtype-specific signatures
Lead Researcher
Markus List, PhD
Lead Institution
Technical University of Munich
Status
Active
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data
Growth hormone signaling in craniopharyngioma
Lead Researcher
Cassie Klein, MD, MAS
Lead Institution
UCSF Benioff Children’s Hospital
Status
Active
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Comparison of RNA-binding protein expressions in pediatric and adult glioblatstoma
Lead Researcher
Xinzhou Zhu, PhD
Lead Institution
"Shenzhen Institute of Advanced Technology, Chinese Academy of Science"
Status
Active
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The Radiogenomics of Molecularly-defined Pediatric Brain Tumors
Lead Researcher
Samantha Pisani, MD, PhD
Lead Institution
"University of California, San Francisco "
Status
Active
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data
DEI Ancestry Project
Lead Researcher
Cassie Klein, MD, MAS
Lead Institution
UCSF Benioff Children’s Hospital
Status
Active
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data
Investigating the Role of ERV Expression in Ependymoma
Lead Researcher
Stephen Mack, PhD
Lead Institution
St. Jude Children's Research Hospital
Status
Active
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Morphological Molecular Correlation of Pediatric Brain Tumors
Lead Researcher
Murad Alturkustani, MD
Lead Institution
"King Abdulaziz University, Jeddah, Saudi Arabia"
Status
Active
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Predicting distant metastasis and chemotherapy benefit in pediatric brain cancer
Lead Researcher
Yan-Ran (Joyce) Wang, MS, PhD
Lead Institution
Stanford University
Status
Active
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data
3D U-Net Segmentation Network for Measurement and Characterization of Pediatric Low-Grade Gliomas
Lead Researcher
Andreas Rauschecker, MD, PhD, MSc
Lead Institution
UCSF Benioff Children’s Hospital
Status
Active
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data
TRK fusion primary CNS tumors
Lead Researcher
Theodore Laetsch, MD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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Mechanistic-based DIPG precision therapy
Lead Researcher
Zeinab Mohamed Mamdouh Abdelkareem Gomaa, M.Sc
Lead Institution
Maastricht University
Status
Active
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Pediatric brain tumor image analytics using AI
Lead Researcher
Neda Haj-Hosseini, PhD
Lead Institution
Linköping University
Status
Active
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data
Automatic segmentation of radiosentitive brain structure in pediatric patients with CNS tumor
Lead Researcher
Marianne Aznar, PhD
Lead Institution
University of Manchester
Status
Active
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data
Molecular signatures underlying radiation resistance in diffuse midline gliomas
Lead Researcher
Thien Nguyen, MD
Lead Institution
"University of California, San Francisco "
Status
Active
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data
Synthetic trial of everolimus in recurrent pediatric LGG patients
Lead Researcher
Sabine Mueller, MD, PhD
Lead Institution
UCSF Benioff Children’s Hospital
Status
Active
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data
PDGFRA expression in K27M gliomas
Lead Researcher
Mariella Filbin, MD, PhD
Lead Institution
Dana-Farber Cancer Institute
Status
Active
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data
Using histopathology to discover genetic alterations in pediatric brain tumors
Lead Researcher
Sabine Mueller, MD, PhD
Lead Institution
UCSF Benioff Children’s Hospital
Status
Active
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data
Multi-institutional analysis of recurrent central nervous system germinomas
Lead Researcher
Mohamed Abdelbaki, MD
Lead Institution
Washington University School of Medicine
Status
Active
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data
Survival outcome of iMB treated without adjuvant craniospinal irradiation: a pooled data analysis in the molecular era
Lead Researcher
Craig Erker, MD, MS, FRCPC
Lead Institution
"IWK Health Centre, Dalhousie University"
Status
Active
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Immune receptor recombinations in childhood brain cancer
Lead Researcher
George Blanck, PhD
Lead Institution
"University of California, San Francisco "
Status
Active
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data
Integrative analyses of data as part of the CFDE
Lead Researcher
Kristin Ardlie, PhD
Lead Institution
Broad Institute
Status
Active
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data
Analyze the relationship between the expression of specific genes and the prognosis in pediatric gliomas.
Lead Researcher
Feng Wan, MD
Lead Institution
"Tongji Hospital, Tongji Medical College, Huazhong University of Science and
Technology"
Status
Active
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Leveraging existing pediatric low-grade tumor specimens, clinical and imaging outcome data and artificial intelligence innovations to develop integrated biomarkers of response for children with low-grade glioma
Lead Researcher
Benjamin H. Kann, MD
Lead Institution
Boston Children's Hospital
Status
Active
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Identification of novel therapeutic approaches for paediatric high-grade gliomas
Lead Researcher
Massimo Squatrito, PhD
Lead Institution
Spanish National Cancer Research Centre
Status
Active
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DIPG International Prevalence of Germline Mutations (DIPG-M)
Lead Researcher
Mark Pinese, PhD
Lead Institution
"Children's Cancer Institute (Sydney, AU)"
Status
Active
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Development of a new therapy against Diffuse Intrinsic Pontine Glioma
Lead Researcher
Terrance Johns
Lead Institution
"Telethon Kids Institute, University of Western Australia"
Status
Active
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data
A Comparison of Hallmark Mutations in Pediatric and Adult Brain Tumors
Lead Researcher
Kevin Judy, MD
Lead Institution
Thomas Jefferson University
Status
Active
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data
Landscape of germline histone mutations in pediatric brain tumor patients
Lead Researcher
Javad Nazarian, PhD
Lead Institution
Children’s National Hospital
Status
Active
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data
Characterizing the blood-brain-barrier in pediatric brain tumors
Lead Researcher
Mark Souweidane, MD
Lead Institution
Weill Cornell Medicine
Status
Active
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Molecular Mechanisms and Functional Impact of Aberrant Splicing in Diffuse Midline Gliomas
Lead Researcher
Ammar Naqvi, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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data
Correlating genomic features with the immune microenvironment in pediatric glioma
Lead Researcher
Robyn Gartrell, MD, MS
Lead Institution
Columbia University
Status
Active
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data
The landscape of pediatric RTK-driven gliomas
Lead Researcher
Ana Guerreiro Stücklin, MD, PhD
Lead Institution
University Children’s Hospital Zürich
Status
Active
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data
Radiogenomic Analysis of Pediatric Brain Tumors
Lead Researcher
Pallavi Tiwari, PhD
Lead Institution
Case Western Reserve University
Status
Active
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data
Genetic risk factors for pediatric brain tumors
Lead Researcher
Anna Dahlin, PhD
Lead Institution
Umeå University
Status
Active
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data
Targeting histone H3K4me3 for the treatment of pediatric gliomas
Lead Researcher
Guifa Xi, PhD
Lead Institution
Northwestern University
Status
Active
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data
Germline determinants of the pediatric tumor immune microenvironment
Lead Researcher
Hannah Carter, PhD
Lead Institution
"University of California, San Diego"
Status
Active
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data
Investigating the etiology of genomic rearrangements in human cancers
Lead Researcher
Xiaotu Ma, PhD
Lead Institution
St. Jude Children's Research Hospital
Status
Active
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specimen
Molecular Characterization of Pediatric Brain Tumor Subjects and Trios within the Pediatric Brain Tumor Atlas
Lead Researcher
Mateusz Koptyra, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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data
Diversity, Equity, and Inclusion: Translation of Informed Consent Forms
Lead Researcher
Cassie Kline, MD, MAS
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
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specimen
Discovering Novel Epigenetic Dependencies in Pediatric High-grade Glioma
Lead Researcher
Mariella Filbin, MD, PhD
Lead Institution
Harvard Medical School
Status
Active
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specimen
Cell Ecosystem and Signaling Pathways of Primary and Metastatic Pediatric Posterior Fossa Ependymoma
Lead Researcher
Pablo G. Cámara, PhD, DABMGG
Lead Institution
University of Pennsylvania
Status
Active
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specimen
Biomarker Identification for Neurofibromatosis Type 2 Background
Lead Researcher
Andrew Mullen, PhD
Lead Institution
NF2 Biosolutions and General Metabolics, LLC
Status
Active
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specimen
Developing a Novel Tumor Model to Screen for New Therapies for Spinal Ependymoma
Lead Researcher
Linda M. Smith-Resar, MD
Lead Institution
Johns Hopkins Medicine
Status
Active
Details
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specimen
Gene Expression Analysis Platform Evaluation for FFPE Specimen Material-Based Studies
Lead Researcher
Mateusz Koptyra
Lead Institution
Children's Hospital of Philadelphia
Status
Complete
Details
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specimen
Whole Genome Sequencing and RNA Sequencing of the CBTN Bank for the Pediatric Brain Tumor Atlas
Lead Researcher
Adam Resnick, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
Details
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data
Integrative Functional Genomics of Recurrent Childhood Medulloblastoma
Lead Researcher
Javad Nazarian, PhD, MSc
Lead Institution
Children’s National Hospital
Status
Active
Details
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data
DIPG and Other Primary Pediatric Brain Tumors
Lead Researcher
Hideho Okada, MD, PhD
Lead Institution
UCSF Benioff Children’s Hospital
Status
Active
Details
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data
Immunotherapeutically-targeting IDO1 in Pediatric High-grade Glioma
Lead Researcher
Derek Wainwright, PhD
Lead Institution
Northwestern University
Status
Complete
Details
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data
Telomere Maintenance Across Multiple Brain Tumors
Lead Researcher
Kristina A. Cole, MD, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
Details
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data
In Silico Neo-antigen Detection in High-grade Pediatric Brain Tumors Utilizing RNA-seq and WGS
Lead Researcher
Peter Madsen, MD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
Details
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specimen
Choroid Plexus Tumor (CPT) Therapies Based on Patient-derived Cell Culture Resources
Lead Researcher
Mark Souweidane, MD
Lead Institution
Weill Cornell Medicine
Status
Active
Details
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data
Fusion Analysis in CBTN RNAseq Data
Lead Researcher
Andrea Sboner, PhD
Lead Institution
Weill Cornell Medicine
Status
Active
Details
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data
Genetic Polymorphisms and Neuro-Cognitive Outcomes in Pediatric Brain Tumor Survivors
Lead Researcher
Matthew Hocking, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
Details
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data
Treehouse Childhood Cancer Initiative: Identification of Therapeutic Leads for Individual Pediatric Cancer Patients via Cancer Analysis
Lead Researcher
David Haussler, PhD
Lead Institution
UC Santa Cruz Treehouse Childhood Cancer Initiative
Status
Active
Details
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data
Children’s Brain Tumor Network Pediatric Brain Tumor Proteomics Pilot
Lead Researcher
Adam Resnick, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
Details
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data
Comprehensive Genomic and Immune Signature Profiling of Ependymoma and Diffuse Intrinsic Pontine Glioma
Lead Researcher
Kathleen M. Schieffer, MLS
Lead Institution
Nationwide Children's Hospital
Status
Active
Details
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specimen
Pediatric Brain Tumor miRNA Profiling for the Cohort of Children’s Brain Tumor Network Specimens
Lead Researcher
Mateusz Koptyra, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
Details
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specimen
Project Hope: High-Grade Glioma-Omics in Pediatric and AYA
Lead Researcher
Adam Resnick, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
Details
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data
Alternative Splicing in CBTN Data
Lead Researcher
Shihao Shen, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
Details
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data
Discover New Therapeutics for DIPG using a Systems-Based Approach
Lead Researcher
Bin Chen, PhD
Lead Institution
Michigan State University
Status
Active
Details
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data
Descriptive “Pharmacogenomics Analysis” of the CBTN PBTA Cohort
Lead Researcher
Angela Waanders, MD, MPH
Lead Institution
Ann & Robert H. Lurie Children’s Hospital of Chicago
Status
Active
Details
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data
Comparison of CBTN Patient Data with Molecularly-Defined Stem Cell Models of Pediatric Brain Tumors
Lead Researcher
Fredrik Swartling, PhD
Lead Institution
Uppsala University, SWEDEN
Status
Active
Details
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data
Landscape of Tumor-infiltrating T-Cell Repertoire of Pediatric Brain Tumors
Lead Researcher
Gary Kohanbash, PhD
Lead Institution
UPMC Children’s Hospital of Pittsburgh
Status
Active
Details
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specimen
Genomic Analysis of Oligodendrogliomas Across Pediatrics, Adolescents and Adults
Lead Researcher
Adam Resnick PhD PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
Details
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data
Defining the Global Impact of Somatic Structural Variation on the Transcriptome of Human Pediatric Brain Cancers
Lead Researcher
Chad Creighton, PhD
Lead Institution
Baylor College of Medicine
Status
Active
Details
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specimen
Oncolytic Virus to Potentiate Immune-checkpoint Blockade in Immunologically Cold Pediatric Brain Tumors
Lead Researcher
Aaron Diaz, PhD
Lead Institution
UCSF Benioff Children’s Hospital
Status
Active
Details
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specimen
Exploring the Possible Role of Mutations in MTOR pathway Genes in the Pathogenesis of DNET Tumors
Lead Researcher
Anna Maria Buccoliero, MD, PhD
Lead Institution
Meyer Children’s Hospital
Status
Active
Details
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data
Cross-disease Variant Lookup in CBTN
Lead Researcher
Yiran Guo, PhD
Lead Institution
Children's Hospital of Philadelphia
Status
Active
Details
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specimen
CBTN Cell Lines High-Throughput Drug Screening Study (NCATS)
Lead Researcher
Mateusz Koptyra, PhD
Lead Institution
Children’s Hospital of Philadelphia
Status
Active
Details
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data
Comprehensive Molecular Profiling of Pediatric Meningioma
Lead Researcher
Kathleen M. Schieffer, MLS
Lead Institution
Nationwide Children's Hospital
Status
Active
Details
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data
Investigating Biomarker for Treatment Respondors and Non-respondors in PDX Model Experiment
Lead Researcher
Mi-Youn Brusniak PhD, PMP
Lead Institution
Fred Hutchinson Cancer Recerch Center
Status
Active
Details
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data
Comprehensive Molecular Profiling of Pediatric Diffuse Astrocytomas: Independent Validation of Proteomic Analysis
Lead Researcher
Kathleen M. Schieffer, MLS
Lead Institution
Nationwide Children's Hospital
Status
Active
Details
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data
A Highly-Usable and Fully-Comprehensive Proteogenomic Method Leveraging the Breadth of Genetic Variation for Oncogenic and/or Therapeutic Novel Protein Discovery
Lead Researcher
Alex Kentsis, MD PhD
Lead Institution
Memorial Sloan-Kettering Cancer Center
Status
Active
Details
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specimen
Microglial Mosaicism in BRAFV600E Glioma Development
Lead Researcher
Estibaliz Lopez-Rodrigo, MD
Lead Institution
Weill Cornell Medicine
Status
Active
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data
Health Disparities of Pediatric Brain Tumors
Lead Researcher
Xiao-Nan Li, MD, PhD
Lead Institution
Ann & Robert H. Lurie Children’s Hospital of Chicago
Status
Active
Details
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data
Proteomic Analysis of CBTN Cell Lines
Lead Researcher
Roger Reddel, MD, BSc (Med), MBBS, FRACP, FAAHMS, FAA
Lead Institution
The University of Sydney
Status
Active
Details
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specimen
Investigating Disease Mechanism In Adamantinomatous Craniopharyngioma Using New Cell Line Models
Lead Researcher
Todd Hankinson, MD
Lead Institution
Children's Hospital of Colorado
Status
Active
Details
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data
Non-coding Genetic Events in Medulloblastoma and Ependymoma
Lead Researcher
Marco Gallo, PhD
Lead Institution
University of Calgary
Status
Active
Details
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data
Aberrant Splicing Candidates as Potential Neoantigen Expression in High-grade Glioma
Lead Researcher
Patrick Pirrotte, PhD
Lead Institution
Translational Genomics Research Institute
Status
Active
Details
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specimen
Functional Dependency Mapping in Paediatric Brain Cancers
Lead Researcher
Ron Firestein, MD, PhD
Lead Institution
Hudson Institute of Medical Research
Status
Active
Details
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data
Identification of Novel Therapeutic Approaches for pHGGs
Lead Researcher
Massimo Squatrito, PhD
Lead Institution
Spanish National Cancer Research Center (CNIO)
Status
Active
Details
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data
Leveraging Existing Pediatric Low-Grade Tumor Specimens, Clinical and Imaging Outcome Data, and Artificial Intelligence Innovations to Develop Integrated Biomarkers of Response for Children With Low-Grade Glioma
Lead Researcher
Benjamin H. Kann, MD
Lead Institution
Harvard Medical School
Status
Active
Details
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data
Analyze the Relationship Between the Expression of Specific Genes and the Prognosis in Pediatric Gliomas
Lead Researcher
Feng Wan, MD
Lead Institution
Tongji Hospital, Tongji Medical College, Huazhong University of Science and
Technology
Status
Active
Details
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specimen
Genetic Vulnerabilities in Supratentorial and Infratentorial Pediatric High-grade Gliomas
Lead Researcher
Massimo Squatrito, PhD
Lead Institution
Spanish National Cancer Research Center (CNIO)
Status
Active
Details
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data
Pediatric Meningiomas
Lead Researcher
Sameer Agnihotri, PhD
Lead Institution
UPMC Children’s Hospital of Pittsburgh
Status
Active
Details
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data
Immune Receptor Recombinations in Childhood Brain
Lead Researcher
George Blanck, PhD
Lead Institution
University of South Florida
Status
Active
Details
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specimen
CDC42 RHOJ Interaction Inhibitors for the Treatment of Neurofibromatosis
Lead Researcher
Anand Ganesan, MD, PhD
Lead Institution
University of California, Irvine
Status
Active
Details
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data
Comparison of RNA-Binding Protein Expressions in Pediatric and Adult Glioblastoma
Lead Researcher
ZHU Xinzhou, PhDShenZhen Institutes of Advanced Technology Chinese Academy of SciencesCBTN Data
Lead Institution
Shenzhen Institutes of Advanced Technology, Chinese Academy of Science