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Empowering Discovery Through Data



Access CBTN Research Resources for Pediatric Brain Tumor Discovery

Data, Specimens, Imaging, and Preclinical Models

CBTN provides researchers with one of the most comprehensive pediatric brain tumor research resources available, including Pediatric Brain Tumor Atlas (PBTA) clinical data, multiomic datasets, imaging data, preclinical models, and thousands of high-quality biospecimens spanning diverse tumor types.

Access follows NIH guidelines. Project requests are subject to review and approval by CBTN’s Scientific Committee for biospecimens and preclinical models to ensure scientific merit and ethical use. The CBTN scientific review process uses a primary and secondary review over a four-week period. The CBTN team will work with the investigator during that time to answer any questions. Controlled-access multiomic data can also be requested via dbGaP. 

CBTN DATA TYPES

Clinical Data
Germline WGS
Somatic WGS
Methylation
RNASeq
Proteomics
Imaging

Questions? Reach help here.

Get Started in a Snap!

1

Submit Request

Complete the Research Resources access request form for review by the CBTN Scientific Committee.

Submit Request
2

Identify Resources

Work with a CBTN expert to identify the specimens, models, or other resources you need.
3

Receive Materials

Materials are delivered to your laboratory free of charge for nonprofit institutions.
4

Connect

Connect with the CBTN research community through office hours, working groups, and more.

Power Up Your Research

The Gabriella Miller Kids First Pediatric Research Program provides researchers with integrated scientific support, combining infrastructure, funding pathways, and collaborative resources to accelerate discovery and drive real-world impact in pediatric brain tumor research.

Discover Funding Opportunities

Get to Know the Platforms Driving Progress

Open Access

PedcBioPortal shares processed data that enables researchers to visualize, explore, and analyze large-scale pediatric cancer genomic datasets. No permissions required.

PedcBioPortal
Open Access

CBTN proteomic data are available through the CPTAC Proteomic Data Commons (PDC). Access to requires dbGaP authorization.

CPTAC Proteomic Data Commons
Controlled Access

dbGaP is an NIH-sponsored repository that distributes data from studies exploring genotype-phenotype relationships. Researchers access controlled datasets by completing the Data Access Application.

Apply for Access
Controlled Access

CAVATICA is a secure, cloud-based platform for storing, sharing, and analyzing massive genomic datasets. With integrated bioinformatics workflows, it fuels real-time collaboration and deep analysis across research teams worldwide. Access CAVATICA through dbGaP.

CAVATICA
Controlled Access

Backed by the NIH, this centralized ecosystem connects genomic data about childhood cancers and birth defects, including CBTN data. Access to CBTN’s controlled molecular data is available through the CBTN dbGaP Study Accession #phs002517.v4.p2.

Kids First Data Resource Center Portal
Controlled Access

This platform brings imaging into the data ecosystem, allowing researchers to analyze deidentified MRI and clinical images. It supports advanced radiomics and AI-powered image analysis. Access Flywheel imaging records through CBTN Research Resources.

Request access
Controlled Access

The world’s largest collection of childhood brain tumor data, the PBTA, was created to bring together rich clinical and genetic information in one shared resource. Complete a CBTN Research Resources (link to the web-friendly form) request to access it.

Learn more
Controlled Access

The CBTN Preclinical Models Portal offers sophisticated models like tumoroids and other patient-derived systems to better understand tumor biology and test promising therapies.

Explore Preclinical Models