Telomere Maintenance Across Multiple Brain Tumors

To keep Chromosomes bundled, telomeres act as caps on the ends of DNA strands. As cells divide, telomeres get shorter causing cell aging and death. It has been demonstrated that the dramatic shortening of telomeres could lead to the ability for cancer to continually grow and divide such as neuroblastoma. In this study, researchers seek to compare genetic information of various high grade gliomas (HGG) with telomere abundance using the Pediatric Brain Tumor Atlas. This knowledge could guide researchers and medical professionals in finding opportunities for new therapies.