Skip to main content

Bold Science for Brighter Futures

FILTERS
All
PBTA Data
CBTN Biospecimen
Reset
data

PDGFRA Expression in K27M Gliomas

Lead Researcher
Mariella Filbin MD, PhD
Lead Institution
Harvard Medical School
Details
Tap for overview
specimen

Molecular Characterization of Pediatric Brain Tumor Subjects and Trios within the Pediatric Brain Tumor Atlas

Lead Researcher
Mateusz Koptyra, PhD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
data

Diversity, Equity, and Inclusion: Translation of Informed Consent Forms

Lead Researcher
Cassie Kline, MD, MAS
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
specimen

Discovering Novel Epigenetic Dependencies in Pediatric High-grade Glioma

Lead Researcher
Mariella Filbin, MD, PhD
Lead Institution
Harvard Medical School
Details
Tap for overview
specimen

Disclosing Chromatin Accessibility in Brain Tumor Cells after Treatment by Cracking a ‘Nucleosomal Code’

Lead Researcher
Jakub Mieczkowski, PhD
Lead Institution
Medical University of Gdansk
Details
Tap for overview
data

DIPG International Prevalence of Germline Mutations (DIPG-M)

Lead Researcher
Mark Pinese, PhD
Lead Institution
Children's Cancer Institute
Details
Tap for overview
specimen

Cell Ecosystem and Signaling Pathways of Primary and Metastatic Pediatric Posterior Fossa Ependymoma

Lead Researcher
Pablo G. Cámara, PhD, DABMGG
Lead Institution
University of Pennsylvania
Details
Tap for overview
specimen

Biomarker Identification for Neurofibromatosis Type 2 Background

Lead Researcher
Andrew Mullen, PhD
Lead Institution
NF2 Biosolutions and General Metabolics, LLC
Details
Tap for overview
specimen

Comparison of Fusion Calling Platforms in Pediatric DIPG and High‐grade Glioma

Lead Researcher
Carl Koschmann, MD
Lead Institution
Michigan Medicine C.S. Mott Children’s Hospital
Details
Tap for overview
specimen

Exploration of IDO1 as a Therapeutic Target in Pediatric Central Nervous System Tumors

Lead Researcher
Rishi Ramesh Lulla, MD
Lead Institution
The Warren Alpert Medical School of Brown University
Details
Tap for overview
specimen

Neurocytoma WGS and RNAseq

Lead Researcher
Adam Resnick, PhD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
specimen

Developing a Novel Tumor Model to Screen for New Therapies for Spinal Ependymoma

Lead Researcher
Linda M. Smith-Resar, MD
Lead Institution
Johns Hopkins Medicine
Details
Tap for overview
specimen

Target Identification and Modeling of NF1-associated Low-grade Glioma

Lead Researcher
Michael J. Fisher, MD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
specimen

Targeting Replicative Stress in Pediatric Brain Tumors with ALT

Lead Researcher
Kristina A. Cole, MD, PhD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
specimen

Gene Expression Analysis Platform Evaluation for FFPE Specimen Material-Based Studies

Lead Researcher
Mateusz Koptyra
Lead Institution
Children's Hospital of Philadelphia
Details
Tap for overview
data

Evaluation of Immunosignature Profile in Medulloblastoma

Lead Researcher
Mateusz Koptyra, PhD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
specimen

Whole Genome Sequencing and RNA Sequencing of the CBTN Bank for the Pediatric Brain Tumor Atlas

Lead Researcher
Adam Resnick, PhD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
data

Proteogenomic Identification of Structural Variations

Lead Researcher
Brian Rood, MD
Lead Institution
Children’s National Hospital
Details
Tap for overview
specimen

Comprehensive Molecular Analysis of Pediatric Thalamic tumors

Lead Researcher
Javad Nazarian, PhD, MSc
Lead Institution
Children’s National Hospital
Details
Tap for overview
specimen

Development of the Ganglioside GD2 as a Biomarker and Clinical Trial Endpoint for Childhood Cancers

Lead Researcher
Frank M. Balis, MD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
data

Integrative Functional Genomics of Recurrent Childhood Medulloblastoma

Lead Researcher
Javad Nazarian, PhD, MSc
Lead Institution
Children’s National Hospital
Details
Tap for overview
data

DIPG and Other Primary Pediatric Brain Tumors

Lead Researcher
Hideho Okada, MD, PhD
Lead Institution
UCSF Benioff Children’s Hospital
Details
Tap for overview
data

Immunotherapeutically-targeting IDO1 in Pediatric High-grade Glioma

Lead Researcher
Derek Wainwright, PhD
Lead Institution
Northwestern University
Details
Tap for overview
data

Analysis of Chromatin Pathways as Regulators of High Grade Glioma Gene Expression Patterns

Lead Researcher
Jamie Anastas, PhD
Lead Institution
Boston Children's Hospital
Details
Tap for overview
data

Telomere Maintenance Across Multiple Brain Tumors

Lead Researcher
Kristina A. Cole, MD, PhD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
data

In Silico Neo-antigen Detection in High-grade Pediatric Brain Tumors Utilizing RNA-seq and WGS

Lead Researcher
Peter Madsen, MD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
specimen

Choroid Plexus Tumor (CPT) Therapies Based on Patient-derived Cell Culture Resources

Lead Researcher
Mark Souweidane, MD
Lead Institution
Weill Cornell Medicine
Details
Tap for overview
specimen

Identifying Tumor Cell Vulnerabilities in Recurrent/Progressive Human Medulloblastomas by Single-cell RNA-seq

Lead Researcher
Ninib Baryawno, PhD
Lead Institution
Karolinska Institutet
Details
Tap for overview
data

Spatial Evolution and Somatic Mutations Spectrum of Gliomatosis Cerebri

Lead Researcher
Jeffrey Greenfield, MD, PhD
Lead Institution
Weill Cornell Medicine
Details
Tap for overview
data

Multi-Tensor Decompositions for Personalized Pediatric Glioma Diagnostics and Prognostics

Lead Researcher
Sri Priya Ponnapalli, PhD
Lead Institution
Eigengene
Details
Tap for overview
data

Integrative Analysis of Childhood Cancers

Lead Researcher
Charlie Vaske, PhD
Lead Institution
NantOmics
Details
Tap for overview
data

Defining the Mutational Landscape of Pediatric Brain Tumors

Lead Researcher
Sharon J. Diskin, PhD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
data

Fusion Analysis in CBTN RNAseq Data

Lead Researcher
Andrea Sboner, PhD
Lead Institution
Weill Cornell Medicine
Details
Tap for overview
data

Cooperating Mutations in Brain Tumors of Patients with NF1

Lead Researcher
Thomas De Raedt, PhD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
data

Genetic Polymorphisms and Neuro-Cognitive Outcomes in Pediatric Brain Tumor Survivors

Lead Researcher
Matthew Hocking, PhD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
data

Molecular Analysis of the Cellular Ecosystem of Childhood Ependymoma

Lead Researcher
Pablo G. Cámara, PhD, DABMGG
Lead Institution
University of Pennsylvania
Details
Tap for overview
data

GPC2 as an Immunotherapeutic Target in Medulloblastoma and Other Pediatric Brain Tumors

Lead Researcher
Kristopher Bosse, MD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
data

Treehouse Childhood Cancer Initiative: Identification of Therapeutic Leads for Individual Pediatric Cancer Patients via Cancer Analysis

Lead Researcher
David Haussler, PhD
Lead Institution
UC Santa Cruz Treehouse Childhood Cancer Initiative
Details
Tap for overview
data

Comparison of Clinical Targeted Next Generation Sequencing (NGS) in FFPE with Whole Genome Sequencing (WGS) of Snap Frozen Pediatric Brain Tumors

Lead Researcher
Bonnie L. Cole, MD
Lead Institution
Seattle Children’s Hospital
Details
Tap for overview
data

Cancer Predisposition in Pediatric Brain Tumors

Lead Researcher
Suzanne P. MacFarland, MD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
specimen

Interactions Between Astrocytes and Tumor Cells Are Critical for Medulloblastoma Growth

Lead Researcher
Suzanne P. MacFarland, MD
Lead Institution
Temple University
Details
Tap for overview
data

Genomic Landscape of Mixed Glial Neuronal Tumors

Lead Researcher
Lea F. Surrey, MD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
data

Cracking the Histone Code: Characterizing Pediatric Brain Tumor Epigenetics using Cerebrospinal Fluid

Lead Researcher
Amanda M. Saratsis, MD
Lead Institution
Ann & Robert H. Lurie Children’s Hospital of Chicago
Details
Tap for overview
data

Identifying New Cell Surface Targets for Immunotherapy Treatment of Poor Prognosis Pediatric Brain Tumors

Lead Researcher
Misty Jenkins, PhD
Lead Institution
Walter and Eliza Hall Institute of Medical Research (WEHI)
Details
Tap for overview
data

Immunogenomic Landscape of Pediatric Cancers

Lead Researcher
Trevor Pugh, PhD, FACMG
Lead Institution
University of Toronto
Details
Tap for overview
data

Identify Novel Therapeutic Targets and Biomarkers in Non-coding Genome of Pediatric Cancers

Lead Researcher
Lihua Zou, PhD
Lead Institution
Northwestern University
Details
Tap for overview
data

Children’s Brain Tumor Network Pediatric Brain Tumor Proteomics Pilot

Lead Researcher
Adam Resnick, PhD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
data

Deciphering the Molecular Characteristics of Pediatric Meningiomas

Lead Researcher
Nadia Dahmane, PhD
Lead Institution
Weill Cornell Medicine
Details
Tap for overview
data

Characterizing the Prevalence of ETMR by Molecular Signature

Lead Researcher
Derek Hanson, MD
Lead Institution
Joseph M. Sanzari Children’s Hospital at Hackensack University Medical Center
Details
Tap for overview
specimen

Development of Preclinical Models of Pediatric Ependymoma

Lead Researcher
Ching Ching Lau, MD, PhD
Lead Institution
Hematology-Oncology at Connecticut Children’s
Details
Tap for overview
data

Comprehensive Genomic and Immune Signature Profiling of Ependymoma and Diffuse Intrinsic Pontine Glioma

Lead Researcher
Kathleen M. Schieffer, MLS
Lead Institution
Nationwide Children's Hospital
Details
Tap for overview
data

Detection of Cooperative and Mutually Exclusive Genetic Alterations in Pediatric Cancer

Lead Researcher
Patrick Kemmeren, PhD
Lead Institution
Princess Maxima Center for Pediatric Oncology
Details
Tap for overview
data

Genomic Correlates with Radiation Injury

Lead Researcher
Oren J. Becher, MD
Lead Institution
Ann & Robert H. Lurie Children’s Hospital of Chicago
Details
Tap for overview
data

Predictive Models for Transcriptome Variations

Lead Researcher
Yoseph Barash, PhD
Lead Institution
University of Pennsylvania
Details
Tap for overview
specimen

Pediatric Brain Tumor miRNA Profiling for the Cohort of Children’s Brain Tumor Network Specimens

Lead Researcher
Mateusz Koptyra, PhD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
data

Hudson Monash Paediatric Precision Medicine Program

Lead Researcher
Ron Firestein, MD, PhD
Lead Institution
Hudson Institute of Medical Research
Details
Tap for overview
specimen

Elucidating the Somatic Epigenetic Landscape of Pediatric Meningioma and Schwannoma

Lead Researcher
Sameer Agnihotri, PhD
Lead Institution
UPMC Children’s Hospital of Pittsburgh
Details
Tap for overview
data

Center for Pediatric Tumor Cell Atlas

Lead Researcher
Kristina A. Cole, MD, PhD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
data

Germline mtDNA Variants and Somatic mtDNA Mutations in Pediatric Brain Tumors

Lead Researcher
Xiaowu Gai, PhD
Lead Institution
Children's Hospital Los Angeles
Details
Tap for overview
specimen

Project Hope: High-Grade Glioma-Omics in Pediatric and AYA

Lead Researcher
Adam Resnick, PhD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
data

Pediatric Brain Tumor Classification and Segmentation Using Transfer Learning from Adult Datasets

Lead Researcher
Roy H. Campbell, PhD
Lead Institution
University of Illinois
Details
Tap for overview
data

Alternative Splicing in CBTN Data

Lead Researcher
Shihao Shen, PhD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
data

Relationships Between Genomic, Imaging, and Histopathologic Characteristics in Pediatric Brain Tumors

Lead Researcher
Benjamin Hartley, MD
Lead Institution
Weill Cornell Medicine
Details
Tap for overview
data

Discover New Therapeutics for DIPG using a Systems-Based Approach

Lead Researcher
Bin Chen, PhD
Lead Institution
Michigan State University
Details
Tap for overview
data

Comprehensive Analysis of Structural Variants in Pediatric Brain Tumors

Lead Researcher
Lixing Yang, PhD, MSc
Lead Institution
University of Chicago
Details
Tap for overview
data

Clinical, Radiologic, and Molecular Characteristics of Anaplastic Pleomorphic Xanthoastrocytomas

Lead Researcher
Alberto Bronisco, MD, MS
Lead Institution
UPMC Children's Hospital of Pittsburgh
Details
Tap for overview
data

Central Nervous System Cancers in Patients with Non-Neurofibromatosis Type 1 RASopathies

Lead Researcher
Alberto Bronisco, MD, MS
Lead Institution
UPMC Children's Hospital of Pittsburgh
Details
Tap for overview
data

Molecular Characterization of Choroid Plexus Tumors

Lead Researcher
Christian Thomas, MD
Lead Institution
Institute of Neuropathology Münster
Details
Tap for overview
data

Germline and Somatic Microsatellite Genotypes in Pediatric Brain Tumors

Lead Researcher
Brian Rood, MD
Lead Institution
Children’s National Hospital
Details
Tap for overview
data

Epigenetic Drivers in Medulloblastoma

Lead Researcher
Alexandros Tzatsos, MD, PhD
Lead Institution
George Washington University
Details
Tap for overview
data

Epigenetic Drivers in Diffuse Intrinsic Pontine Gliomas (DIPG)

Lead Researcher
Alexandros Tzatsos, MD, PhD
Lead Institution
George Washington University
Details
Tap for overview
data

Descriptive “Pharmacogenomics Analysis” of the CBTN PBTA Cohort

Lead Researcher
Angela Waanders, MD, MPH
Lead Institution
Ann & Robert H. Lurie Children’s Hospital of Chicago
Details
Tap for overview
data

Comparison of CBTN Patient Data with Molecularly-Defined Stem Cell Models of Pediatric Brain Tumors

Lead Researcher
Fredrik Swartling, PhD
Lead Institution
Uppsala University, SWEDEN
Details
Tap for overview
data

Body Mass Index Trajectories in Craniopharyngioma

Lead Researcher
Shana McCormack, MD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
data

Landscape of Tumor-infiltrating T-Cell Repertoire of Pediatric Brain Tumors

Lead Researcher
Gary Kohanbash, PhD
Lead Institution
UPMC Children’s Hospital of Pittsburgh
Details
Tap for overview
data

Evaluating the Landscape of Compound Heterozygous Variants in Pediatric Diseases

Lead Researcher
Stephen Piccolo, PhD
Lead Institution
Brigham Young University
Details
Tap for overview
data

PNOC and SJCRH Collaborative DIPG Radiogenomic Investigation

Lead Researcher
John Lucas, MD, MS
Lead Institution
St. Jude Children's Research Hospital
Details
Tap for overview
data

Molecular and Functional Characterization of Childhood Supratentorial Ependymoma

Lead Researcher
Vijay Ramaswamy, MD, PhD, FRCPC
Lead Institution
Sick Kids
Details
Tap for overview
specimen

Genomic Analysis of Oligodendrogliomas Across Pediatrics, Adolescents and Adults

Lead Researcher
Adam Resnick PhD PhD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
data

Cancer Stemness of Pediatric Tumors

Lead Researcher
Maciej Wiznerowicz, MD, PhD
Lead Institution
International Institute for Molecular Oncology
Details
Tap for overview
data

Targeting Immunosuppressive Macrophage in Pediatric Brain Tumors

Lead Researcher
Erin Crotty, MD
Lead Institution
Seattle Children's Hospital
Details
Tap for overview
data

Detecting Gene Fusions and Subtype Discovery in Pediatric Solid Tumors RNA-Seq using CICERO

Lead Researcher
Scott Newman, PhD
Lead Institution
St. Jude Children's Research Hospital
Details
Tap for overview
data

Defining the Global Impact of Somatic Structural Variation on the Transcriptome of Human Pediatric Brain Cancers

Lead Researcher
Chad Creighton, PhD
Lead Institution
Baylor College of Medicine
Details
Tap for overview
specimen

Oncolytic Virus to Potentiate Immune-checkpoint Blockade in Immunologically Cold Pediatric Brain Tumors

Lead Researcher
Aaron Diaz, PhD
Lead Institution
UCSF Benioff Children’s Hospital
Details
Tap for overview
specimen

Germline and Somatic Determinants of Paediatric Brain Tumor Evolution

Lead Researcher
Sorana Morrissy, PhD
Lead Institution
University of Calgary
Details
Tap for overview
specimen

Exploring the Possible Role of Mutations in MTOR pathway Genes in the Pathogenesis of DNET Tumors

Lead Researcher
Anna Maria Buccoliero, MD, PhD
Lead Institution
Meyer Children’s Hospital
Details
Tap for overview
data

Cross-disease Variant Lookup in CBTN

Lead Researcher
Yiran Guo, PhD
Lead Institution
Children's Hospital of Philadelphia
Details
Tap for overview
specimen

Elucidating the Role of Driver Mutations in Pediatric High Grade Glioma

Lead Researcher
Thomas De Raedt, PhD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
specimen

Elucidate Potential Therapeutic Targets in H3.3G34 Mutant pHGG Cells

Lead Researcher
Zhiguo Zhang, PhD
Lead Institution
Columbia University
Details
Tap for overview
specimen

CBTN Cell Lines High-Throughput Drug Screening Study (NCATS)

Lead Researcher
Mateusz Koptyra, PhD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
data

Genomics of Radiation-induced Cavernomas in Pediatric Tumor Patients

Lead Researcher
YouRong Sophie Su MD, DO
Lead Institution
University of Pennsylvania
Details
Tap for overview
data

Comprehensive Molecular Profiling of Pediatric Meningioma

Lead Researcher
Kathleen M. Schieffer, MLS
Lead Institution
Nationwide Children's Hospital
Details
Tap for overview
data

Multi-scale Model of Children with Brain Tumors

Lead Researcher
Olivier Gevaert, PhD
Lead Institution
Stanford University
Details
Tap for overview
data

The Australian Bioinformatics Commons Paediatric Cancer Pathfinder Project

Lead Researcher
Mark Cowley, BSc, PhD
Lead Institution
Children's Cancer Institute
Details
Tap for overview
data

Developing Summative Measures of Paediatric Cancer Risk

Lead Researcher
Mark Cowley, BSc, PhD
Lead Institution
Children's Cancer Institute
Details
Tap for overview
data

Decoding the Dark Matter of the High-Risk Paediatric Cancer Genome

Lead Researcher
Mark Cowley, BSc, PhD
Lead Institution
Children's Cancer Institute
Details
Tap for overview
data

Investigating Biomarker for Treatment Respondors and Non-respondors in PDX Model Experiment

Lead Researcher
Mi-Youn Brusniak PhD, PMP
Lead Institution
Fred Hutchinson Cancer Recerch Center
Details
Tap for overview
data

Comprehensive Molecular Profiling of Pediatric Diffuse Astrocytomas: Independent Validation of Proteomic Analysis

Lead Researcher
Kathleen M. Schieffer, MLS
Lead Institution
Nationwide Children's Hospital
Details
Tap for overview
data

A Highly-Usable and Fully-Comprehensive Proteogenomic Method Leveraging the Breadth of Genetic Variation for Oncogenic and/or Therapeutic Novel Protein Discovery

Lead Researcher
Alex Kentsis, MD PhD
Lead Institution
Memorial Sloan-Kettering Cancer Center
Details
Tap for overview
data

Novel Neoantigen Detection from Complex Transcriptomic Structures in Pediatric Brain Tumors

Lead Researcher
Tamer Ahmed, MD, PhD
Lead Institution
University of California - Davis
Details
Tap for overview
data

Defining the Role of the Histone 3 (H3.3G34R) Mutation in the Pathogenesis of Pediatric High Astrocytoma

Lead Researcher
Cynthia Hawkins, MD, PhD, FRCPC
Lead Institution
Sick Kids
Details
Tap for overview
specimen

Microglial Mosaicism in BRAFV600E Glioma Development

Lead Researcher
Estibaliz Lopez-Rodrigo, MD
Lead Institution
Weill Cornell Medicine
Details
Tap for overview
specimen

Therapeutic Targeting of the Blood-Brain Barrier in Pediatric Malignant Brain Tumors

Lead Researcher
Sadhana Jackson, MD
Lead Institution
National Cancer Institute, National Institute of Health
Details
Tap for overview
specimen

Targeting Medulloblastoma by Regulating RNA Binding Proteins

Lead Researcher
Robert Schnepp, MD, PhD
Lead Institution
Emory University
Details
Tap for overview
specimen

Released Tumor DNA in the CSF for the Diagnosis and Monitoring of Pediatric Brain Tumors

Lead Researcher
Chetan Bettegowda, MD, PhD
Lead Institution
Johns Hopkins Medicine
Details
Tap for overview
data

Mitochondrial Mutations in Pediatric Brain Cancer

Lead Researcher
Paul Boutros, Ph.D., M.B.A
Lead Institution
University of California, Los Angeles
Details
Tap for overview
data

Splicing Analysis in Ependymoma

Lead Researcher
Marcel Kool, PhD
Lead Institution
Hopp Children's Cancer Center
Details
Tap for overview
specimen

Regional Response to ONC201 in Pediatric High-Grade Glioma

Lead Researcher
Carl Koschmann, MD
Lead Institution
Michigan Medicine C.S. Mott Children’s Hospital
Details
Tap for overview
specimen

Using Whole Genome Bisulfite Sequencing to Identify Novel Therapeutic Targets in DIPG and ATRT

Lead Researcher
Eric Raabe, MD, PhD
Lead Institution
Johns Hopkins Medicine
Details
Tap for overview
data

The Role of Mutational Signatures in the Development of Childhood Cancer

Lead Researcher
Michael E. Scheurer, PhD, MPH, FACE
Lead Institution
Baylor College of Medicine
Details
Tap for overview
data

iPC EU Horizon 2020 – Individualized Paediatric Cure: Cloud-based Virtual-patient Models for Precision Paediatric Oncology

Lead Researcher
Dejan Stepec, MS
Lead Institution
XLAB d.o.o.
Details
Tap for overview
data

Exploring the Somatic Landscape of Adult and Paediatric Chordoma

Lead Researcher
Adrienne Flanagan, PhD, FRCPath, BCh, BAO, LRCPI, LRCSI, FMed Sci
Lead Institution
University College London Cancer Institute
Details
Tap for overview
data

Health Disparities of Pediatric Brain Tumors

Lead Researcher
Xiao-Nan Li, MD, PhD
Lead Institution
Ann & Robert H. Lurie Children’s Hospital of Chicago
Details
Tap for overview
specimen

Impeding LIN28 Function in ATRT

Lead Researcher
Giselle Saulnier Sholler, MD
Lead Institution
Levine Children's Cancer & Blood Disorders
Details
Tap for overview
data

Mechanistic Modeling of High-grade Glioma

Lead Researcher
Dr Christoph Wierling
Lead Institution
Alacris Theranostics GmbH
Details
Tap for overview
data

The Role of Genetic Factors in Ependymoma Susceptibility

Lead Researcher
Maral Adel Fahmideh, PhD
Lead Institution
Baylor College of Medicine
Details
Tap for overview
specimen

Identification of Circulating Noncoding RNAs and Metabolites in Cerebrospinal Fluid(CSF) in Medulloblastoma Patients

Lead Researcher
Ranjan Perera, PhD
Lead Institution
Johns Hopkins Medicine
Details
Tap for overview
specimen

Circular RNAs in Medulloblastoma

Lead Researcher
Peter George Zaphiropoulos, PhD
Lead Institution
Karolinska Institutet
Details
Tap for overview
data

Cross-Species Omics Integration to Identify Oncogenic Events in Pediatric Brain Tumors

Lead Researcher
Junmin Peng, PhD
Lead Institution
St. Jude Children's Research Hospital
Details
Tap for overview
data

Proteomic Analysis of CBTN Cell Lines

Lead Researcher
Roger Reddel, MD, BSc (Med), MBBS, FRACP, FAAHMS, FAA
Lead Institution
The University of Sydney
Details
Tap for overview
data

Brain Match

Lead Researcher
Stefan M. Pfister, MD
Lead Institution
Hopp Children's Cancer Center
Details
Tap for overview
specimen

Investigating Disease Mechanism In Adamantinomatous Craniopharyngioma Using New Cell Line Models

Lead Researcher
Todd Hankinson, MD
Lead Institution
Children's Hospital of Colorado
Details
Tap for overview
data

Pediatric Pan-Cancer Analysis of Structural Variants

Lead Researcher
Lukas Chavez, PhD
Lead Institution
University of California, San Diego
Details
Tap for overview
data

Genetic Variability Across Major Histocompatibility Complex

Lead Researcher
Tristan J Hayeck, PhD
Lead Institution
Children's Hospital of Philadelphia
Details
Tap for overview
data

A Study of Outcomes in Patients with CNS Tumors with BCOR Mutations

Lead Researcher
Scott Raskin, DO
Lead Institution
Children's National Hospital
Details
Tap for overview
data

Determining Prognostic Factors and Genetic Markers that Impact Survival in Recurrent Pediatric Medulloblastoma

Lead Researcher
Chetan Bettegowda, MD, PhD
Lead Institution
Johns Hopkins Medicine
Details
Tap for overview
data

Sex-specific Gene Expression Signatures in Pediatric Brain Tumors

Lead Researcher
Joshua B. Rubin, MD, PhD
Lead Institution
St. Louis Children’s Hospital
Details
Tap for overview
data

Non-coding Genetic Events in Medulloblastoma and Ependymoma

Lead Researcher
Marco Gallo, PhD
Lead Institution
University of Calgary
Details
Tap for overview
data

Genetic Architecture of Molecular Phenotypes in Pediatric Brain Cancers

Lead Researcher
Sebastian Waszak, PhD
Lead Institution
University of Oslo
Details
Tap for overview
data

Mechanisms of Medulloblastoma Formation

Lead Researcher
Erwin G. Van Meir, PhD
Lead Institution
University of Alabama at Birmingham (UAB)
Details
Tap for overview
data

Targeting Regions of Converging Synteny in Pediatric and Canine Glioma

Lead Researcher
Roel Verhaak, PhD
Lead Institution
The Jackson Laboratory
Details
Tap for overview
specimen

Investigating the Metabolic Hallmarks of Oligodendroglioma

Lead Researcher
Samuel McBrayer, PhD
Lead Institution
Children’s Medical Center Research Institute at UT Southwestern
Details
Tap for overview
data

Artificial Intelligence for Pediatric Brain Tumor Detection and Prediction of Disease Progression

Lead Researcher
Patrick Hales, PhD
Lead Institution
University College London
Details
Tap for overview
data

Investigating the Immune Response in Pediatric Glioma Subsets

Lead Researcher
Joanna Phillips MD, PhD
Lead Institution
UCSF Benioff Children’s Hospital
Details
Tap for overview
data

Detecting Driver Mutations of Central Nervous System Germ Cell Tumors

Lead Researcher
Jiguang Wang, PhD
Lead Institution
HONG KONG University of Science and Technology
Details
Tap for overview
data

Aberrant Splicing Candidates as Potential Neoantigen Expression in High-grade Glioma

Lead Researcher
Patrick Pirrotte, PhD
Lead Institution
Translational Genomics Research Institute
Details
Tap for overview
data

Aberrant Splicing Candidates as Potential Neoantigen Expression in HGG

Lead Researcher
Patrick Pirrotte, PhD
Lead Institution
The Translational Genomics Research Institute
Details
Tap for overview
data

Searching for Differences in Molecular Profile of Pediatric Gliomas

Lead Researcher
Nikolay Ivanov, BS
Lead Institution
Weill Cornell Medicine
Details
Tap for overview
data

Identifying the Cells of Origins of Brain Tumors Using Somatic Mutations

Lead Researcher
Gilad Evrony, MD, PhD
Lead Institution
Hassenfeld Children’s Hospital at NYU Langone
Details
Tap for overview
specimen

Delineating Pediatric Glioma Progression Using Single-nuclei Sequencing

Lead Researcher
Trevor Pugh, PhD, FACMG
Lead Institution
University of Toronto
Details
Tap for overview
data

Structural Variants in Human and Canine Cancer Datasets

Lead Researcher
Charles Lee, Ph.D., D.Sc., FACMG, FRSC
Lead Institution
The Jackson Laboratory
Details
Tap for overview
data

Targeting Master Regulator Dependencies in Diffuse Intrinsic Pontine Glioma (DIPG)

Lead Researcher
Javad Nazarian,PhD, MSc
Lead Institution
Children’s National Hospital
Details
Tap for overview
specimen

Personalized Therapy for High-risk Ependymoma of Childhood

Lead Researcher
Vijay Ramaswamy, MD, PhD, FRCPC
Lead Institution
Sick Kids
Details
Tap for overview
specimen

Functional Dependency Mapping in Paediatric Brain Cancers

Lead Researcher
Ron Firestein, MD, PhD
Lead Institution
Hudson Institute of Medical Research
Details
Tap for overview
data

Precision Imaging of Pediatric High-grade Gliomas with Quantitative Diffusion Weighted Imaging and Texture Analysis to Identify Imaging Biomarkers That Predict Tumor Genetics and Patient Outcomes

Lead Researcher
Mariam Aboian, MD, PhD
Lead Institution
Yale School of Medicine
Details
Tap for overview
specimen

Use of Ependymoma Cell Lines to Test for New Therapeutic Vulnerabilities

Lead Researcher
Marcel Kool, PhD
Lead Institution
Hopp Children's Cancer Center
Details
Tap for overview
data

Development of a New Therapy Against Diffuse Intrinsic Pontine Glioma

Lead Researcher
Terrance Johns, PhD
Lead Institution
The University of Western Australia
Details
Tap for overview
data

Identification of Novel Therapeutic Approaches for pHGGs

Lead Researcher
Massimo Squatrito, PhD
Lead Institution
Spanish National Cancer Research Center (CNIO)
Details
Tap for overview
data

A Comparison of Hallmark Mutations in Pediatric and Adult Brain Tumors

Lead Researcher
Kevin D Judy, MD
Lead Institution
Thomas Jefferson University Hospital
Details
Tap for overview
data

Leveraging Existing Pediatric Low-Grade Tumor Specimens, Clinical and Imaging Outcome Data, and Artificial Intelligence Innovations to Develop Integrated Biomarkers of Response for Children With Low-Grade Glioma

Lead Researcher
Benjamin H. Kann, MD
Lead Institution
Harvard Medical School
Details
Tap for overview
data

Landscape of Germline Histone Mutations in Pediatric Brain Tumor Patients

Lead Researcher
Javad Nazarian, PhD, MSc
Lead Institution
Children’s National Hospital
Details
Tap for overview
specimen

Oncogene-Induced Senescence in RTK-fused Infant High Grade Gliomas

Lead Researcher
David Kram, MD, MCR
Lead Institution
UNC Chapel Hill – North Carolina Children’s Hospital
Details
Tap for overview
data

Characterizing the Blood-Brain-Barrier in Pediatric Brain Tumors

Lead Researcher
Nadia Dahmane PhD
Lead Institution
Weill Cornell Medicine
Details
Tap for overview
data

Analyze the Relationship Between the Expression of Specific Genes and the Prognosis in Pediatric Gliomas

Lead Researcher
Feng Wan, MD
Lead Institution
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Details
Tap for overview
specimen

Investigating the Tumorigenesis Mechanisms and Vulnerabilities of Pediatric High-grade Gliomas with H3G34R/V

Lead Researcher
Yang Shi, PhD
Lead Institution
Harvard Medical School
Details
Tap for overview
specimen

Genetic Vulnerabilities in Supratentorial and Infratentorial Pediatric High-grade Gliomas

Lead Researcher
Massimo Squatrito, PhD
Lead Institution
Spanish National Cancer Research Center (CNIO)
Details
Tap for overview
specimen

MET Alterations in DMGs

Lead Researcher
Payal Jain, PhD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
data

Pediatric Meningiomas

Lead Researcher
Sameer Agnihotri, PhD
Lead Institution
UPMC Children’s Hospital of Pittsburgh
Details
Tap for overview
data

Molecular Mechanisms and Functional Impact of Aberrant Splicing in Diffuse Midline Gliomas

Lead Researcher
Ammar Naqvi, PhD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
specimen

Elucidating Heterogeneity of Resistance Across Molecular Subgroups of Pediatric Ependymomas to Inform Future Therapeutics

Lead Researcher
Jeffrey Greenfield, MD, PhD
Lead Institution
Weill Cornell Medicine
Details
Tap for overview
data

Correlating Genomic Features with the Immune Microenvironment in Pediatric Glioma

Lead Researcher
Robyn Gartrell, MD, MS
Lead Institution
Columbia University
Details
Tap for overview
data

The Landscape of Pediatric RTK-Driven Gliomas

Lead Researcher
Ana Guerreiro Stücklin, MD, PhD
Lead Institution
University Children’s Hospital Zürich
Details
Tap for overview
data

Radiogenomic Analysis of Pediatric Brain Tumors

Lead Researcher
Pallavi Tiwari, PhD, MS
Lead Institution
Case Western Reserve University
Details
Tap for overview
data

Genetic Risk Factors for Pediatric Brain Tumors

Lead Researcher
Anna Dahlin
Lead Institution
Umeå University
Details
Tap for overview
data

Immune Receptor Recombinations in Childhood Brain

Lead Researcher
George Blanck, PhD
Lead Institution
University of South Florida
Details
Tap for overview
data

Targeting Histone H3K4me3 for the Treatment of Pediatric Gliomas

Lead Researcher
Guifa Xi, MD, PhD
Lead Institution
Ann & Robert H. Lurie Children’s Hospital of Chicago
Details
Tap for overview
specimen

RP58 and SMARCB1 in AT/RT Pathogenesis

Lead Researcher
Nadia Dahmane, PhD
Lead Institution
Weill Cornell Medicine
Details
Tap for overview
specimen

Evaluation of Drug Vulnerability of NF2 Tumor Models

Lead Researcher
Joseph Kissil, PhD
Lead Institution
Moffitt Cancer Center
Details
Tap for overview
data

Germline Determinants of the Pediatric Tumor Immune Microenvironment

Lead Researcher
Hannah Carter, PhD
Lead Institution
University of California, San Diego
Details
Tap for overview
data

Investigating the Etiology of Genomic Rearrangements in Human Cancers

Lead Researcher
Xiaotu Ma, PhD
Lead Institution
St. Jude Children's Research Hospital
Details
Tap for overview
specimen

Pre-clinical Studies for NF2 Schwannomas

Lead Researcher
Christina Fernandez-Valle, PhD
Lead Institution
University of Central Florida
Details
Tap for overview
specimen

CDC42 RHOJ Interaction Inhibitors for the Treatment of Neurofibromatosis

Lead Researcher
Anand Ganesan, MD, PhD
Lead Institution
University of California, Irvine
Details
Tap for overview
data

Using Histopathology to Discover Genetic Alterations in Pediatric Brain Tumors

Lead Researcher
Sabine Mueller, MD, PhD
Lead Institution
UCSF Benioff Children’s Hospital
Details
Tap for overview
data

High Dimensional Protein Characterization of Tumor Tissues and Relevance to Outcomes in Immunotherapy Clinical Trials

Lead Researcher
Kristina A. Cole, MD, PhD
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
specimen

Establishing a Thalamic Glioma Model

Lead Researcher
Javad Nazarian, PhD, MSc
Lead Institution
Children’s National Hospital
Details
Tap for overview
specimen

Novel Platforms for Developing Therapies for Transformed Gliomas in Patients with NF1

Lead Researcher
Javad Nazarian, PhD, MSc
Lead Institution
Children’s National Hospital
Details
Tap for overview
specimen

Evaluating NF2 and Other Tumor Disease Mechanisms

Lead Researcher
Javad Nazarian, PhD, MSc
Lead Institution
Children’s National Hospital
Details
Tap for overview
specimen

Elucidating the ETMR Microenvironment Using Next Generation Imaging and Multi-omics Technologies

Lead Researcher
Claire Carter, PhD
Lead Institution
Joseph M. Sanzari Children’s Hospital at Hackensack University Medical Center
Details
Tap for overview
data

Multi-Institutional Analysis of Recurrent Central Nervous System Germinomas

Lead Researcher
Mohamed AbdelBaki, MD
Lead Institution
St. Louis Children’s Hospital
Details
Tap for overview
specimen

Development of CAR-T Cell Therapy for Atypical Teratoid/Rhabdoid Tumors

Lead Researcher
Peter Madsen, M.D. Children’s Hospital of Philadelphia Philadelphia, PA, USA CBTN Specimen
Lead Institution
Children’s Hospital of Philadelphia
Details
Tap for overview
data

Comparison of RNA-Binding Protein Expressions in Pediatric and Adult Glioblastoma

Lead Researcher
ZHU Xinzhou, PhDShenZhen Institutes of Advanced Technology Chinese Academy of SciencesCBTN Data
Lead Institution
Shenzhen Institutes of Advanced Technology, Chinese Academy of Science
Details
Tap for overview
data

MI-ONCOSEQ DMG Study

Lead Researcher
Carl Koschmann, MD
Lead Institution
Michigan Medicine C.S. Mott Children’s Hospital
Details
Tap for overview
0 Results.
Please broaden your search.

Reset

Project Title

Status

Lead Researcher

Lead Institution

Overview