Characterizing the blood brain pediatric brain tumors

Because these tumors are very rare, the CBTN is an invaluable resource for studying these diseases. Furthermore, the genomic resources for pediatric brain tumors are incomparable. We will include all patients with MRI available within the CBTN (n=243) for preliminary analysis, though only those with T1 pre-contrast, T1 post-contrast, and T2-FLAIR sequences will be included in the analysis (expect around one-third to qualify). We will also include any additional patients with these MRI sequences that are successfully requested. A large cohort is necessary to find statistically significant associations, particularly when adjusting for false discovery for genomic correlates.