Correlating Genomic Features with the Immune Microenvironment in Pediatric Glioma

Brain cancers cause more childhood deaths than any other type of cancer, especially high-grade glioma (HGG) which is incurable and low grade glioma (LGG) which causes decreased quality of life. New treatment methods using the immune system (which is composed of cells that are involved in fighting infection), called immunotherapies, offer promise for LGG and HGG in children. In order to use immunotherapy in childhood glioma, it is important that we understand the immune system response to these tumors