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Development of Preclinical Models of Pediatric Ependymoma

The incidence of pediatric ependymoma is low. In order to expedite the development of these preclinical models so that they could also be used for preclinical drug development, we are trying to identify as many existing cases as possible. Since CBTTC currently has the largest collection of childhood brain tumor specimens that are available for collaborative research, we are therefore very interested in exploring the possibility of utilizing what are currently banked and also that our request to use live or cryopreserved tissues be considered as one of the priorities for future specimens that will be submitted.

In addition to CBTTC, we have collaborative relationship with several other institutions that will also provide fresh tissues for this study including Connecticut Children’s Medical Center where Dr. Lau is currently Chief of Hematology and Oncology.