DIPG and Other Primary Pediatric Brain Tumors

Gene expression, the process by which the genetic information is used to direct production of proteins in the body, is crucial in understanding the similarities and differences across tumor types and across same-type tumor mutations. Beginning with gliomas with H3K27M mutations, researchers will investigate genes related to the immune system and their possible role in future immunotherapy, treatments that use a patient’s own immune system to attack a tumor. Access to the Pediatric Brain Tumor Atlas will give researchers important data for these investigations.