Discover new therapeutics for DIPG using a systems-based approach:

Novel approaches are urgently needed to treat Diffuse intrinsic pontine glioma (DIPG) . We hypothesize that reversing signature gene expression derived from DIPG RNA-Seq samples will facilitate novel therapeutic discovery for DIPG. We therefore request the raw RNA-Seq FASTQ files to build DIPG gene expression signature which will be fed into our computational pipeline to identify potential candidates, followed by experimental validation.