Elucidating Heterogeneity of Resistance Across Molecular Subgroups of Pediatric Ependymomas to Inform Future Therapeutics

We are interested in looking at functional differences in resistance between molecular subgroups of ependymomas in order to inform future therapeutics. We would like to study 2-4 cell lines from each of the subgroups most common in children, specifically PF-EPN-A, ST EPN-RELA, ST-EPN-YAP1. Ependymoma tumors are rare in children and ependymoma cell lines are difficult to establish: thus, we are requesting existing cell lines to conduct this important research.