Immunogenomic Landscape of Pediatric Cancers

The study of a tumor’s immune repertoire includes an analysis of T cell receptors and B cell receptors that allow an immune system to adapt to changes and launch an immune system response. Understanding the immune repertoire of pediatric tumors could lead to advancements in immunotherapy, a therapy that uses a patient’s own immune system to attack a tumor. Researchers will analyze data from pediatric brain tumors through access to the Pediatric Brain Tumor Atlas in a search for relevant features of the immune system that could be utilized in new immunotherapies.