Neurocytoma WGS and RNAseq

For this project, tumors of the specific diagnoses of neurocytoma were identified for whole-genome and RNA sequencing. Whole genome sequencing involves identifying all of the base chemicals that make up the DNA in a genome. RNA sequencing involves analyzing for the presence and quantity of RNA. Both of these analyses are integral in the field of cancer biology and cancer treatment because they help researchers better understand how a tumor forms, grows, and persists. The goal of this project is to perform whole genome and RNA sequencing on neurocytomas. The Children’s Brain Tumor Network contributed to the project by providing germline and tumor DNA and tumor RNA for use by investigators. The information gained from this work could lead to advances in treatment for patients with neurocytoma.