Proteogenomic Identification of Structural Variations

We request 10-15 mg of FF tumor tissue for proteomic peptide sequencing for 40 MB tumors RNA-Seq data from the same samples for the construction of custom search databases Germline and Tumor WGS data from the same patients to confirm structural variations and screen out normal variants Blood DNA from 5 subjects for pilot ddPCR detection of ctDNA containing tumor specific SVs CSF for DNA isolation and pilot ddPCR detection of ctDNA containing tumor specific SVs.