Treehouse Childhood Cancer Initiative: Identification of Therapeutic Leads for Individual Pediatric Cancer Patients via Cancer Analysis

The information stored in DNA dictates how cells make proteins and other molecules. Cancer alters this gene expression, resulting in tumors. Oncogenes, genes with the potential to cause cancer, can be utilized in the treatment of cancer itself but they must first be identified. Using the Pediatric Brain Tumor Atlas, researchers are comparing data across many forms of pediatric brain cancers. Through the comparison of gene expression across tumor types and individual patients using RNA sequencing, researchers are building an open-access resource for others to guide therapeutic decisions. For more information visit the Treehouse Project.