Worldwide Collaboration Advancing Hope

Intermountain Primary Children’s Hospital is a nationally ranked leader in pediatric care and the only Level I Pediatric Trauma Center in the Intermountain West. As the teaching hospital for the University of Utah, it serves families across one of the largest geographic areas in the U.S.

With a strong focus on research and innovation, the hospital supports more than 1,000 studies each year and provides advanced care through programs like the Sorenson Center for Cancer & Blood Disorders. Treating over 100 new brain and CNS tumor cases annually and offering dozens of active neuro-oncology trials, Primary Children’s advances CBTN’s mission to deliver better treatments and brighter futures for kids.

Akron Children’s Hospital provides care to more than one million patients each year across its network. Its certified oncology team treats a range of childhood cancers and blood disorders, caring for approximately eight newly diagnosed cancer patients each month. As a member of the Children’s Oncology Group (COG) and one of the few pediatric programs verified by the American College of Surgeons Commission on Cancer, Akron Children’s helps shape national standards of care, contributing to CBTN’s goal of advancing treatments and improving outcomes for children.

The University of Iowa Stead Family Children’s Hospital is the state’s only comprehensive children’s hospital, offering services that span general wellness, trauma, surgery, chronic conditions, and developmental disabilities, providing comprehensive pediatric care for families across Iowa.

As part of an academic medical center, the hospital drives research into childhood diseases and trains the next generation of healthcare professionals, embracing CBTN’s vision to improve the lives of children with brain tumors.

As both a care provider and a research hub, UNC Children’s Hospital integrates academic medicine with a commitment to families, advancing discovery, education, and treatment in alignment with CBTN’s mission to improve outcomes for children. UNC Children’s brings together nearly 200 physician faculty from the UNC School of Medicine, spanning 50 programs across 20 clinical departments, including 14 divisions of pediatrics. Supported by more than 1,800 clinical and ancillary staff, the hospital delivers expert, compassionate care to thousands of children each year.

Johns Hopkins All Children’s Hospital delivers personalized care for children with brain and spinal tumors, using precision medicine to guide treatments based on each tumor’s genetic and molecular profile. Advanced neuro-imaging and complex surgical expertise are paired with a focus on preserving motor skills, vision, hearing, and cognition.

Backed by the Cancer & Blood Disorders Institute and the Institute for Brain Protection Sciences, the program integrates expertise through collaborative tumor boards and clinical trials. Strengthened by affiliation with the H. Lee Moffitt Cancer Center & Research Institute, Johns Hopkins All Children’s advances CBTN’s mission to improve outcomes for children facing brain tumors.

The Aflac Cancer and Blood Disorders Center at Children’s Healthcare of Atlanta is one of the nation’s largest pediatric brain tumor programs, caring for more than 750 children each year. Its specialists provide comprehensive treatment that includes advanced neurosurgery, radiation, chemotherapy, stem cell transplantation, and clinical trials for resistant or relapsed cancers. Researchers at Aflac are also driving discovery in the lab, developing new therapies to target the deadliest brain tumors. By pairing leading science with compassionate, child-focused care, the center plays a critical role in advancing CBTN’s mission to deliver cures for pediatric brain tumors.

Nicklaus Children’s Hospital is South Florida’s leading pediatric referral center, caring for nearly 70% of the region’s children. Its Centers of Excellence in cancer, neuroscience, orthopedics, and heart care are supported by a state-of-the-art surgical tower and robust transfer and transport programs that save nearly 5,000 lives each year. As home to the Southeast’s most extensive pediatric teaching program and an ANCC Magnet-designated facility since 2003, Nicklaus Children’s advances both excellence in care and the education of future pediatric leaders, strengthening CBTN’s global mission to improve outcomes for children with brain tumors.

Texas Children’s Hospital in Houston is one of the nation’s largest and most distinguished pediatric centers, consistently ranked among the top children’s hospitals in the U.S. As the primary pediatric teaching hospital of Baylor College of Medicine and a cornerstone of the Texas Medical Center, it combines world-class clinical care with leading education and research. Through its scale, expertise, and commitment to discovery, Texas Children’s Hospital plays a vital role in advancing CBTN’s mission to accelerate cures and improve outcomes for children with brain tumors.

As a partner in CBTN’s mission to drive discovery and improve outcomes for children, Maria Fareri Children’s Hospital in Valhalla, NY, delivers advanced pediatric care through the Hudson Valley’s only Level I pediatric trauma and burn center and its only Level IV NICU.

The hospital offers expertise across various specialties, including neurology and oncology. Committed to family-centered care, Maria Fareri Hospital involves families in every stage of treatment while providing private rooms and supportive therapy programs. In partnership with New York Medical College, it also advances research, education, and training for the next generation of pediatric providers.

St. Louis Children’s Hospital (SLCH), founded in 1879 and affiliated with Washington University School of Medicine, is a nationally ranked pediatric center with 258 beds and Magnet® designation for nursing excellence. Its Pediatric Neuro-Oncology Center provides comprehensive care for brain and spinal cord tumors, offering advanced technologies such as intra-operative MRI and proton beam radiation. In collaboration with the Siteman Cancer Center, SLCH leads basic, translational, and clinical research supported by robust tumor banking and genomic resources, advancing CBTN’s mission to deliver better outcomes for children worldwide.

The Pediatric Neuro-Oncology Program at OHSU Doernbecher Children’s Hospital is nationally recognized for excellence in cancer and neurosurgery and stands as a leading center on the West Coast. As part of the Pacific Pediatric Neuro-Oncology Consortium (PNOC), the program helps drive forward new therapies for children with brain and spinal cord tumors.

Care is delivered through a fully integrated team, ensuring every patient and family receives comprehensive, personalized treatment. Through this collaborative approach, OHSU Doernbecher advances CBTN’s vision of uniting expertise and discovery to improve outcomes for children.

The University Children’s Hospital Zurich is the largest pediatric hospital in Switzerland and one of Europe’s leading centers for pediatric care and research. Its Oncology Department, part of the Comprehensive Cancer Center Zürich, collaborates with ETH Zurich to advance discovery and innovation.

With deep expertise in clinical trials and international consultations, the team is shaping therapies for some of the most challenging brain tumors, including diffuse intrinsic pontine glioma, other gliomas, and medulloblastomas. Through its research leadership, Zurich contributes to CBTN’s goal of delivering improved treatments and outcomes for children with brain tumors.

The Kids Cancer Centre (KCC) at Sydney Children’s Hospital, Randwick cares for children with cancer and blood disorders across New South Wales, Australia, and the Asia-Pacific region. By bridging research and care, the Kids Cancer Centre strengthens CBTN’s mission to accelerate progress and bring new hope to children worldwide. Through its Early Phase Clinical Trials Centre, KCC works with scientists, clinicians, industry partners, and global collaborators to bring promising laboratory discoveries into the clinic. With a focus on children whose cancers resist standard treatments or lack effective cures, the center opens Phase I and Phase II trials to provide access to emerging therapies.

C.S. Mott Children’s Hospital is a leader in treating relapsed and resistant cancers, running Michigan’s largest pipeline of Phase 1 trials and one of the nation’s most advanced gene sequencing programs to deliver personalized therapies. It also operates the state’s largest pediatric bone marrow transplant and cellular therapy programs.

The Chad Carr Pediatric Brain Tumor Center, established in 2018, has become a national hub for high-risk brain tumors. As part of the Pacific Neuro-Oncology Consortium (PNOC) and through sequencing with the MiOncoseq program, the center advances new therapies and shares data internationally via the Children’s Brain Tumor Network.

For more than 30 years, Orlando Health Arnold Palmer Hospital for Children has delivered expert, compassionate care to families across Central Florida and beyond. Home to the region’s only pediatric Level One Trauma Center and Emergency Department, the hospital combines advanced technology with a team dedicated to putting children’s health first. Through this commitment, it supports CBTN’s mission to unite care and discovery to improve patient outcomes.

By combining breadth of care with a commitment to discovery, Hassenfeld Children’s Hospital contributes to CBTN’s mission of improving outcomes for children everywhere. With over 400 physicians, Hassenfeld offers a comprehensive range of services to patients in the New York City region, from routine treatments to highly complex interventions. Beyond clinical excellence, the hospital advances pediatric health through research on environmental impacts, health literacy, and childhood obesity, while offering families access to clinical trials.

As a driving force in pediatric neuro-oncology, Weill Cornell Medicine partners with other CBTN institutions to unite science and care for children with brain tumors. Its Clinical Neuro-Oncology Program treats hundreds of patients each year, connecting them to advanced therapies and innovative clinical trials. By integrating developmental biology, immunotherapy, precision medicine, and novel drug delivery research, its Children’s Brain Tumor Project accelerates the path to breakthrough treatments and potential cures.

Known for top-ranked programs in pediatrics, cancer, cardiology, transplants, and specialized care, Atrium Health delivers innovation and compassion at scale. Through Wake Forest School of Medicine, the system’s academic core, Atrium advances experiential medical education, biomedical discovery, and new medical technologies. By combining expansive clinical reach with research leadership, Atrium Health contributes to CBTN’s mission of transforming care for children everywhere.

The Neuro-Oncology Program at UPMC Children’s Hospital is a national leader in developing new treatments for pediatric brain and nervous system cancers. Patients gain access to leading-edge clinical trials for brain and spine tumors, supported by research across hematology, oncology, and neuro-oncology. Led by experts such as Dr. Ian Pollack, the team’s high-grade glioma studies exemplify how laboratory discoveries translate directly into improved therapies. By advancing both innovation and care, UPMC strengthens CBTN’s mission to deliver brighter futures for children with brain tumors.

The Treehouse Childhood Cancer Initiative is a champion for open data sharing, ensuring that discoveries move swiftly from analysis to the clinic. Through this approach, it contributes to CBTN’s vision of accelerating precision medicine and expanding treatment options for children with cancer. Treehouse also harnesses large-scale genomic data from both pediatric and adult cancers to identify potential treatments tailored to each child’s tumor. By analyzing across vast datasets, researchers can pinpoint when existing drugs may be effective for a specific patient.

The Pediatric Brain Tumor Center at UCSF Benioff Children’s Hospital treats more than 100 children each year and connects families to innovative trials through the Pacific Pediatric Neuro-Oncology Consortium (PNOC). Its researchers are advancing new ways to deliver therapies across the blood-brain barrier, including convection-enhanced delivery and ultrasound, while also leading immunotherapy trials for aggressive tumors such as diffuse midline gliomas. With this expertise, UCSF drives CBTN’s mission to bring breakthrough treatments to children worldwide.

Lucile Packard Children’s Hospital Stanford, housed within Stanford Children’s Health, is nationally ranked for excellence in pediatrics and obstetrics. Its Pediatric Neuro-Oncology Program brings together a multidisciplinary team using advanced, minimally invasive techniques, including ROSA™ robotic-assisted surgery. The hospital leads more than a dozen brain tumor clinical trials. By uniting expert care with groundbreaking research, Packard Children’s propels CBTN’s mission to accelerate cures for children with brain tumors.

Through its scale, expertise, and commitment to discovery, Children’s of Alabama strengthens the CBTN mission to accelerate cures and deliver better outcomes. Children’s of Alabama is the only medical center in the state dedicated solely to pediatric care, and it stands among the largest pediatric medical facilities in the U.S. As the teaching hospital for UAB’s pediatric programs, its care is powered by a team of faculty, full-time physicians, and community doctors working together.

Seattle Children’s Hospital hosts the largest pediatric brain tumor program in the Northwestern U.S. and is internationally recognized for its expertise in CNS tumors. It has been ranked among the nation’s best children’s hospitals for more than 25 years, and its Cancer and Blood Disorders Center has been a top pediatric oncology program for over a decade.

Patients gain access to advanced neurosurgery, proton therapy, and leading clinical trials, while researchers drive innovative studies including CAR T cell therapies for difficult-to-treat tumors. As a key contributor to CBTN, Seattle Children’s pairs world-class care with transformative research to advance cures for kids.

Integrated with the University of Florence, Meyer Children’s Hospital combines advanced care, research, and training to serve children across Italy and beyond. With 250 beds and expertise spanning all pediatric medical and surgical specialties, Meyer stands as a national referral center within the Italian health system. Meyer strengthens the shared global mission of CBTN to accelerate breakthroughs in the treatment of pediatric brain tumors.

Advancing the CBTN mission, Hackensack Meridian Children’s Health brings world-class care and discovery to children with brain and spinal cord tumors. Its Pediatric Neuro-Oncology Program combines cutting-edge research and clinical trials with comprehensive treatment delivered by a multidisciplinary team of specialists. The hospital is home to New Jersey’s only nationally ranked pediatric cancer program, placed among the top 50 in the U.S. The Joseph M. Sanzari Children’s Hospital has also achieved repeated national recognition for pediatric neurology and neurosurgery, affirming its leadership in complex pediatric care.

Johns Hopkins Medicine, based in Baltimore, unites the Johns Hopkins University School of Medicine with a broad network of hospitals, research institutes, and care facilities. With six hospitals, dozens of patient care centers, and global partnerships, Johns Hopkins delivers care and drives discovery at a scale few can match. As part of CBTN, Johns Hopkins brings its legacy of innovation and collaboration to the fight against pediatric brain tumors, turning world-class expertise into hope for children everywhere.

At the Hudson Institute in Melbourne, science is always moving toward solutions. From discoveries in inflammation and cancer to breakthroughs in reproductive and child health, Hudson’s researchers are shaping the future of care. The Hudson Monash Paediatric Precision Medicine Program zeroes in on childhood brain cancers and solid tumors, translating laboratory insights into new, targeted therapies. By contributing its strengths in precision medicine and translational research, Hudson expands the reach of CBTN, helping transform bold ideas into better outcomes for kids.

The China National GeneBank (CNGB) in Shenzhen, operated by BGI-Research, is China’s first national gene bank and a global leader in conserving, digitizing, and applying genetic resources. As a public, nonprofit platform, CNGB champions the idea that genetic resources should be shared for the benefit of all. Through CBTN, CNGB brings this vision to pediatric brain tumor research, strengthening global collaboration and accelerating discovery for children worldwide.

Dayton Children’s Hospital serves more than 280,000 patients each year, with its neurosurgery team performing over 200 complex procedures annually—some offered at only a few centers nationwide. Through partnerships with Miami Valley Hospital, Wright State University, and Premier Health, Dayton Children’s connects patients to cutting-edge neuroscience research and advanced treatments, advancing the CBTN mission to deliver better outcomes for kids.

Innovation defines the Brain Tumor Institute at Children’s National. Its experts have pioneered molecularly targeted therapies, vaccines, T-cell immunotherapies, and less invasive surgical techniques, reshaping how pediatric brain tumors are treated worldwide. Each year, the institute evaluates more than 100 new patients, delivering comprehensive care backed by leading-edge research. Children’s National is also recognized among the nation’s top hospitals for pediatric cancer. By combining discovery with compassionate care, Children’s National advances the shared mission of CBTN to accelerate breakthroughs and improve outcomes for every child facing a brain tumor.

Innovation and collaboration define care for children with brain tumors at Lurie Children’s. Its Brain Tumor Center has pioneered advanced treatments such as proton therapy while connecting families to a wide range of clinical trials. Weekly, a multidisciplinary Brain Tumor Board reviews patient cases to ensure that every child benefits from the combined expertise of leading specialists, and it treats more than 220 new pediatric cancer patients annually. Uniting world-class expertise with compassion, Laurie Children’s embodies CBTN’s mission to accelerate discovery and deliver better outcomes for kids.

The Children’s Hospital of Philadelphia (CHOP) is a global leader in pediatric brain tumor research and care, and the Operations Center home for the Children’s Brain Tumor Network. CHOP houses the world’s largest pediatric brain and CNS tumor biorepository, fueling discovery on a global scale. With one of the largest pediatric neuro-oncology teams in the U.S., CHOP delivers highly personalized care informed by genomic analysis to tailor treatments for each child. The hospital also drives innovation through clinical trials and pioneering research in genomics, immunotherapy, and molecular medicine.

As China’s most renowned neurosurgical hospital, Beijing Tiantan Hospital Neurosurgery Center (BTHNC) provides children access to unrivaled neurological expertise. Each year, its surgeons perform up to 700 operations to treat the full spectrum of brain and spinal tumors in children.

BTHNC is recognized not only for its volume and precision, but also for its leadership in shaping the future of pediatric neurosurgery in China. As a member institution, the center expands the reach of CBTN’s mission, ensuring that the fight for cures is global, and every child’s life has the chance to be transformed.