Cross-species omics integration to identify oncogenic events in pediatric brain tumors

Our goal is to integrate mouse and human multi-omics data to identify oncogenic events in pediatric brain tumors. In our recent study, we profiled transcriptome, whole proteome and phosphoproteome in two glioma mouse models. We plan to use whole genome sequence and RNAseq data of pediatric brain cancer tissues and perform a cross-species comparisons with mouse data that we collected.