Gene expression correlates of High grade versus low grade Glioma

We will examine RNA-seq dataset to define gene expression correlates distinguishing high grade from low grade pediatric glioma, and see how mRNA correlates relate to protein correlates as obtained using CPTAC data. We will compare the glioma-associated molecular correlates with correlates of high grade versus low grade cancer for other cancer types (e.g. lung, renal). We will identify any associated pathways represented by common molecular correlates.