Investigating somatic mutations in the normal tissues of neurofibromatosis type 1

To assess the generalizability of our observations, it is essential that we acquire additional normal tissue from other patients with neurofibromatosis type 1. This is very rarely collected, and we have yet to identify any other eligible donors. We have normal brain, brain tumour, blood, skin, and multiple intra-abdominal viscera from a single child but it is important we study as many of these tissues in more individuals as possible.