Proteomics X01

This project will generate quantitative proteomics data include post-translational modification data for phospho-, acetyl-, methyl-, and ubiquito- proteomics on at least 406 padiatric brain tumor samples. These cohorts will include craniopharyngioma, medulloblastoma, ependymoma, ATRT and CNS sarcomas. Analysis will be performed in both inter- and intra- histologic diagnosis contexts by teams including bioinformatic support and content experts drawn from the CBTN/PNOC working groups and the wider research community.