Spatial Evolution and Somatic Mutations Spectrum of Gliomatosis Cerebri

The treatment of gliomatosis cerebri and other high grade gliomas (HGG) such as diffuse intrinsic pontine gliomas (DIPG) and ependymoma relies on a comprehensive understanding of each tumor type. Utilizing advancements in computational biology, researchers will use the Pediatric Brain Tumor Atlas and other open access datasets to map the characteristics, growth, progression, metastasis of gliomatosis cerebri and various HGG. This information will deepen the understanding of HGG, guiding tumor assessment, treatment decisions and therapeutic developments.