Choroid Plexus Carcinoma (Grade III)

Choroid Plexus Tumors

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Summary of

Choroid Plexus Carcinoma (Grade III)

Choroid plexus tumors occur in both children and adults, but are more common in children in the first year of life. Choroid plexus tumors occur slightly more often in females than males.

The cause of most choroid plexus tumors is not known. Genetic changes have been linked to the formation of some choroid plexus tumors. Rarely, certain gene changes that can be passed down through families have been linked to a higher chance of developing choroid plexus carcinomas.

Choroid plexus tumors arise from a structure in the brain called the choroid plexus. It lines the ventricles (fluid-filled cavities) of the brain and its primary function is to produce cerebrospinal fluid (CSF). Choroid plexus tumors almost always form within the ventricles. They can also form in other regions of the CNS.

Source: NCI https://www.cancer.gov/rare-brain-spine-tumor/tumors/choroid-plexus-tumors

available Choroid Plexus Tumors

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How many participants are enrolled?

24Participants Enrolled

Available CBTN Biospecimens

participants with flash-frozen tissue available22

participants with flash-frozen tissue available

participants with match blood9

participants with match blood

participants with match parental specimens0

participants with match parental specimens

participants with cerebral spinal fluid0

participants with cerebral spinal fluid

Available CBTN Pre-clinical Models

genomically characterized cell lines with data available0

genomically characterized cell lines with data available

genomically characterized pdx with data available0

genomically characterized pdx with data available

Projects supported by the CBTN

Data projects supported0

Data projects supported

Specimen projects supported0

Specimen projects supported

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How do I get access to the specimens?

To request any of the biospecimens, or pre-clinical model please fill out this form.
Request take approx. 3 months and will require review by the scientific committee and MTA.
Need help? Contact us at research@cbtn.org

How do I get access to the data?

To access the data please follow these instructions. Need help? Contact us at research@cbtn.org
You can access processed data today here by simply logging in to PedcBioPortal
You can request raw data by completing this form. The review normally takes 1 week. Once approved you can access the raw data by creating cohorts of interest on the Kids First Data Resource Portal and performing analysis on the cloud in Cavatica

Flash frozen tissue is tissue from a surgical procedure where the tissue is frozen instantly in liquid nitrogen to ensure there is no degradation

Tissue in freezing media is tissue from a surgical procedure where the tissue is frozen 1 degree at a time over a 24-hour period to keep the tissue intact and compatible with regrowing the tumor for testing

Matched blood is blood that is collected from the patient in addition to tissue from the tumor. This blood provides researchers a direct comparison between normal and tumor specimens for this specific patient

Cerebral Spinal Fluid (CFS) is fluid taken from the the nervous system that researchers can use to study brain tumors

Paternal and maternal specimens are specimens taken from the biological parents of the subject. These specimens provide researchers with the ability to compare tumor and normal tissue and predispositions