enrolled participants

Data Projects Supported
Specimen Projects Supported
Explore Projects

Summary of


Ganglioglioma presents during childhood and into adulthood. It most commonly arises in the cerebral cortex and is associated with seizures, but also presents in other sites, including the spinal cord.[65,74]

The unifying theme for the molecular pathogenesis of ganglioglioma is genomic alterations leading to MAPK pathway activation.[42,75] BRAF alterations are observed in approximately 50% of ganglioglioma cases, with V600E being by far the most common alteration; however, other BRAF mutations and gene fusions are also observed. Other less commonly altered genes in ganglioglioma include KRAS, FGFR1/2, RAF1, NTRK2, and NF1.[42,75]

Available CBTN Biospecimens

participants with flash-frozen tissue available172

participants with flash-frozen tissue available

participants with match blood82

participants with match blood

participants with match parental specimens14

participants with match parental specimens

participants with cerebral spinal fluid0

participants with cerebral spinal fluid

Available CBTN Pre-clinical Models

genomically characterized cell lines with data available1

genomically characterized cell lines with data available

genomically characterized pdx with data available0

genomically characterized pdx with data available

How do I get access to the specimens?

To request any of the biospecimens, or pre-clinical model please fill out this form.
Request take approx. 3 months and will require review by the scientific committee and MTA.
Need help? Contact us at

Explore the data in these informatics portals

How do I get access to the data?

To access the data please follow these instructions. Need help? Contact us at
You can access processed data today here by simply logging in to PedcBioPortal
You can request raw data by completing this form. The review normally takes 1 week. Once approved you can access the raw data by creating cohorts of interest on the Kids First Data Resource Portal and performing analysis on the cloud in Cavatica