Germinoma

Germinoma

Germinoma.png
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Data Projects Supported
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Specimen Projects Supported
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Summary of

Germinoma

Germinomas are the most common type of CNS germ cell tumor and have a good prognosis.

Germ cells are special types of cells that are present as the fetus (unborn baby) develops. These cells usually become sperm in the testicles or unfertilized eggs in the ovaries as the child matures. Most germ cell tumors form in the testes or ovaries. Sometimes the germ cells travel to or from other parts of the fetus as it develops and later become germ cell tumors. Germ cell tumors that form in the brain or spinal cord are called CNS (central nervous system) germ cell tumors.

CNS germ cell tumors occur most often in patients aged 10 to 19 years and more often in males than in females. The most common places for one or more CNS germ cell tumors to form is in the brain near the pineal gland and in an area of the brain that includes the pituitary gland and the tissue just above it. Sometimes germ cell tumors form in other areas of the brain.

Source NCI

Available CBTN Biospecimens

participants with flash-frozen tissue available18

participants with flash-frozen tissue available

participants with match blood11

participants with match blood

participants with match parental specimens6

participants with match parental specimens

participants with cerebral spinal fluid3

participants with cerebral spinal fluid

Available CBTN Pre-clinical Models

genomically characterized cell lines with data available0

genomically characterized cell lines with data available

genomically characterized pdx with data available0

genomically characterized pdx with data available

How do I get access to the specimens?

To request any of the biospecimens, or pre-clinical model please fill out this form.
Request take approx. 3 months and will require review by the scientific committee and MTA.
Need help? Contact us at research@cbtn.org

Explore the data in these informatics portals

How do I get access to the data?

To access the data please follow these instructions. Need help? Contact us at research@cbtn.org
You can access processed data today here by simply logging in to PedcBioPortal
You can request raw data by completing this form. The review normally takes 1 week. Once approved you can access the raw data by creating cohorts of interest on the Kids First Data Resource Portal and performing analysis on the cloud in Cavatica