Detection of Cooperative and Mutually Exclusive Genetic Alterations in Pediatric Cancer

Email Principal Investigator
All Brain Tumor Types
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Patrick Kemmeren

Princess Maxima Center for Pediatric Oncology
Utrecht, Netherlands, Amsterdam



CBTN Participants


Dutch Cancer Foundation

About this


Changes that occur in genes are called genetic alterations. Understanding the genetic interactions of pediatric brain cancers and how they are altered in the genomes of patients could lead to better diagnostics, therapies, and ongoing assessments. Researchers will use data from the Pediatric Brain Tumor Atlas to test genetic interactions in individual cancer types and broadly across all cancer types. This research will create a broad dataset that will be invaluable in the continued pursuit of new treatment techniques and therapies.

Ask The


Ask the scientists

What are the goals of this project?

Researchers seek to develop and analyze a broad set of data on the genetic alterations of many types of pediatric brain tumors.

What is the impact of this project?

This research will study a broad set of pediatric brain cancers, contributing greatly to the body of genetic information necessary to develop new therapeutics.

Why is the CBTN request important to this project?

The Pediatric Brain Tumor Atlas contains specimens across all pediatric brain tumor types, contributing to the broad impact of this project.

Specimen Data

The Children's Brain Tumor Network contributed to this project by providing access to the Pediatric Brain Tumor Atlas.

Explore the data in these informatics portals