Searching for Differences in Molecular Profile of Pediatric Gliomas

Childhood brain cancer is a devastating disease that is still poorly understood. Glioma is a type of brain cancer in which a specific type of cells in the brain (called glial cells), become cancerous. In our study, we will examine how the DNA in glioma cells varies between different groups of patients. We will also study how these differences in DNA affect gene expression. This will allow us to gain a greater understanding of how pediatric glioma develops, how it differs between patients, and how childhood glioma differs from adult glioma. In our research, we will utilize RNA sequencing data from pediatric gliomas from the CBTTC datasets to examine glioma gene expression.