The proposed research study will attempt to create a larger, retrospective review of patients with CNS tumors and BCOR mutations. We hope to learn more about how tumors with BCOR mutations behave and understand more about the differences in tumor types and outcomes including PFS and OS.
What are the goals of this project?
The design of our study is to complete a retrospective chart review of patients with CNS tumors containing BCOR mutations to study differences in outcomes based on genetic variants, tumor type, age, or treatment regimens.
What is the impact of this project?
Hopefully this data will enable us to publish a review of CNS tumors with BCOR mutations and gain an understanding of best treatment regimens for tumors with BCOR mutations as well as understand expected PFS/OS.
The Children's Brain Tumor Network contributed to this project by providing access to the Pediatric Brain Tumor Atlas.