Classification of Pediatric Gangliomas Based on the Histological Infiltration

Abstract

Ganglioglioma is a low-grade glioneuronal tumor with many known morphologies. Morphology refers to the shape and growth pattern of the tumor. This work aimed to bring clarity to the various growth patterns in ganglioglioma. Using imagery and samples provided by CBTN, researchers interrogated growth patterns found in patients with ganglioglioma. This work confirmed the presence of an infiltrative/diffuse variant of ganglioglioma as a significant pattern. Diffuse glioneuronal tumors are used to describe such tumors whose growth infiltrates surrounding areas in the brain. Awareness of this ganglioglioma growth pattern will be important in the continued effort to find new treatments.