Proteogenomic Characterization of 2002 Human Cancers Reveals Pan-Cancer Molecular Subtypes and Associated Pathways
Yiqun Zhang, Fengju Chen, Darshan S. Chandrashekar, Sooryanarayana Varambally, Chad J. Creighton
![graphsCBTN.webp](https://cbtn-s3.imgix.net/graphsCBTN.webp?auto=format&ixlib=react-9.0.3&w=700)
Abstract
With the inclusion of RNA sequencing data provided by CBTN, researchers assembled a dataset of over 2000 tumors across 14 cancer types. Using this dataset, the research team identified 11 distinct tumor types, including 2 subtypes enriched for brain tumors. This pan-cancer survey reveals interplay between the genome and proteome of cancer types found throughout the body and deepens the overall understanding of how brain tumors develop and grow.