Puberty Status Modifies the Effects of Genetic Variants, Lifestyle Factors and Their Interactions on Adiponectin: The BCAMS Study
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Yunpeng Wu, Ling Zhong, Ge Li, Lanwen Han, Junling Fu, Yu Li, Lujiao Li, Qian Zhang, Yiran Guo, Xinhua Xiao, Lu Qi, Ming Li, Shan Gao, Steven. M. Willi
Abstract
Hypoadiponectinemia has been associated with various cardiometabolic disease states. Previous studies in adults have shown that adiponectin levels were regulated by specific genetic and behavioral or lifestyle factors. However, little is known about the influence of these factors on adiponectin levels in children, particularly as mitigated by pubertal development.