Head of Bioinformatics and Modeling
Max Planck Institute for Molecular Genetics
The Systems Biology Group has its research interests in the mathematical modeling of cellular processes with respect to complex diseases, such as cancer. Within the group different systems biology resources and tools for the modeling and simulation of biological systems have been designed and implemented. These tools are used in current projects for the modeling of cancer-related signal transduction and metabolic pathways, their subsequent gene regulatory network, and the effect of mutations and drugs. Moreover, the group is working on the modeling of stem cell biology. The research is driven by the integration of diverse ‘omics data, as generated by current (high-throughput) technologies.