Professor Clinical Research Division, Fred Hutch; Jennifer Lynn Kranz, Unravel Pediatric Cancer Endowed Chair Fred Hutch
Fred Hutchinson Cancer Research Center
James M. Olson, MD, PhD, is attending physician at Seattle Childrens Hospital and member of Fred Hutchinson Cancer Research Center (FHCRC); he is professor of Pediatric Hematology-Oncology and adjunct professor of Pathology at the University of Washington School of Medicine and on the faculty in the Program in Molecular and Cellular Biology, the Program in Neurobiology and Behavior, and the Center for Nanotechnology.
He serves as assistant program head of the pediatric oncology program at FHCRC and has mentored more than 30 graduate students and postdoctoral research fellows. He is chair of a national phase III clinical trial for high-risk medulloblastoma/PNET patients and member of the COG Biology and Translational Research Committee. Olson is principal investigator on six projects that focus on developing effective new therapies for pediatric brain tumors, methods that allow surgeons to better visualize the border of brain cancer and normal brain, and the molecular mechanisms of brain development.
Seattle Children's Hospital
Imipridones affect tumor bioenergetics and promote cell lineage differentiation in diffuse midline gliomas
Researchers analyze the anticancer mechanisms of imipridone ONC201 and lay the groundwork for new clinical trials.
Justyna M Przystal, Chiara Cianciolo Cosentino, Sridevi Yadavilli, Jie Zhang, Sandra Laternser, Erin R Bonner, Rachna Prasad, Adam A Dawood, Nina Lobeto, Wai Chin Chong, Matt C Biery, Carrie Myers, James M Olson, Eshini Panditharatna, Bettina Kritzer, Sulayman Mourabit, Nicholas A Vitanza, Mariella G Filbin, Geoffry N de Iuliis, Matthew D Dun, Carl Koschmann, Jason E Cain, Michael A Grotzer, Sebastian M Waszak, Sabine Mueller, Javad Nazarian