Research Assistant Professor
Ann & Robert H. Lurie Children’s Hospital of Chicago
Dr. Hashizume's primary research interests in understanding of the molecular mechanisms, that affect the aggressive/ invasive biological behavior of pediatric malignant glioma and would accordingly reveal potential therapeutic targets for glioma therapy.
Identify novel therapeutic targets and biomarkers in non-coding genome of pediatric cancers
To identify novel therapeutic targets of pediatric, we conducted an unbiased meta-analysis of gene signatures from multiple public datasets including the Cancer Genome Atlas (TCGA) Low-grade Glioblastoma. Our preliminary work identified a gene network centered on the FoxM1 transcription factor. F