Professor, Departments of Neurology, Pediatrics, and Neurological Surgery,
UCSF Benioff Children's Hospital
Dr. Weiss’s research focuses on developing and characterizing mouse models that faithfully recapitulate the biology and genetics of human tumors of the nervous system, and using observations in the mouse to inform the biology, genetics, and therapy of human tumors.
Specifically, the Weiss Laboratory develops and uses in vivo models for neural cancers to:
- Identify the genetic events that promote tumorigenesis
- Study cancer stem and progenitor cells to understand their contribution to malignant progression
- Evaluate new targets, therapies, and mechanistic rationales for combining targeted agents