Atypical Teratoid/Rhabdoid Tumor
(AT/RT)
Summary of
Atypical Teratoid/Rhabdoid Tumor
Central nervous system (CNS) atypical teratoid/rhabdoid tumor (AT/RT) is a very rare, fast-growing tumor of the brain and spinal cord. It usually occurs in children aged three years and younger, although it can occur in older children and adults. About half of these tumors form in the cerebellum or brain stem. The cerebellum is the part of the brain that controls movement, balance, and posture. The brainstem controls breathing, heart rate, and the nerves and muscles used in seeing, hearing, walking, talking, and eating. AT/RT may also be found in other parts of the central nervous system (brain and spinal cord). The WHO 2016 classification indicates Embryonal tumor.
Available CBTN Biospecimens
97participants with flash-frozen tissue available
62participants with match blood
5participants with match parental specimens
8participants with cerebral spinal fluid
Available CBTN Pre-clinical Models
11genomically characterized cell lines with data available
0genomically characterized pdx with data available
How do I get access to the specimens?
To request any of the biospecimens, or pre-clinical model please fill out this form.
Request take approx. 3 months and will require review by the scientific committee and MTA.
Need help? Contact us at research@cbtn.org
Explore the data in these informatics portals
How do I get access to the data?
To access the data please follow these instructions. Need help? Contact us at research@cbtn.org
You can access processed data today here by simply logging in to PedcBioPortal
You can request raw data by completing this form. The review normally takes 1 week. Once approved you can access the raw data by creating cohorts of interest on the Kids First Data Resource Portal and performing analysis on the cloud in Cavatica
