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Summary of


Ependymomas arise from ependymal cells that line the ventricles and passageways in the brain and the center of the spinal cord. Ependymal cells produce cerebrospinal fluid (CSF). These tumors are classified as supratentorial or infratentorial. In children, most ependymomas are infratentorial tumors that arise in or around the fourth ventricle. The 2016 WHO classifcation indicated one genetically defined ependymoma subtype has been accepted: Ependymoma, RELA fusion–positive [33, 36]. This variant accounts for the majority of supratentorial tumors in children. (Louis DN, 2019)

Available CBTN Biospecimens

participants with flash-frozen tissue available348

participants with flash-frozen tissue available

participants with match blood167

participants with match blood

participants with match parental specimens22

participants with match parental specimens

participants with cerebral spinal fluid14

participants with cerebral spinal fluid

Available CBTN Pre-clinical Models

genomically characterized cell lines with data available8

genomically characterized cell lines with data available

genomically characterized pdx with data available1

genomically characterized pdx with data available

How do I get access to the specimens?

To request any of the biospecimens, or pre-clinical model please fill out this form.
Request take approx. 3 months and will require review by the scientific committee and MTA.
Need help? Contact us at research@cbtn.org

Explore the data in these informatics portals

How do I get access to the data?

To access the data please follow these instructions. Need help? Contact us at research@cbtn.org
You can access processed data today here by simply logging in to PedcBioPortal
You can request raw data by completing this form. The review normally takes 1 week. Once approved you can access the raw data by creating cohorts of interest on the Kids First Data Resource Portal and performing analysis on the cloud in Cavatica