Within specific pediatric brain tumor types, there can be various genetic mutations that could have effects on the ongoing neurological health of pediatric brain cancer survivors. These genetic differences are referred to as genetic polymorphisms. Combining genetic data from the Pediatric Brain Tumor Atlas with measures of cognitive, emotional, social and behavioral functioning of pediatric brain cancer survivors, researchers will assess the affect specific polymorphisms may have on patient outcomes. This study will provide valuable information to inform the clinical care of pediatric brain cancer survivors most at risk for developing neurological issues post-treatment.
What are the goals of this project?
Researchers seek to identify polymorphisms, or genetic differences within tumor types, that could have great impacts on the neurological functioning of pediatric brain cancer survivors.
What is the impact of this project?
The information gained from this project will inform clinical care of pediatric brain cancer survivors, specifically those with tumor mutations that put them at risk for developing issues post-treatment.
Why is the CBTN request important to this project?
Researchers will collect data on the neurological health of pediatric brain cancer survivors, and the data from the Pediatric Brain Tumor Atlas will be crucial for project analysis.
The Children's Brain Tumor Network contributed to this project by providing access to the Pediatric Brain Tumor Atlas
Children’s Hospital of PhiladelphiaJoined on
Operations Center for the Children’s Brain Tumor Tissue Consortium, the Children’s Hospital of Philadelphia (CHOP) is currently ranked 1st nationally for their Pediatric Cancer Program by U.S. News & World Report. CHOP’s Biobank is home to the CBTTC’s pediatric brain and CNS tumor biorepository; the