Associate Professor of Physiology and Biophysics
Weill Cornell Medicine
Current Research Interest: New biochemical and computational methods in functional genomics; novel techniques in next-generation sequencing; algorithms for tumor evolution, genome evolution, DNA and RNA modifications; algorithms for genome/epigenome engineering; international standards for clinical-quality genome measurements/editing; integrated molecular portraits of genomes, epigenomes, transcriptomes, and metagenomes for NASA astronauts to establish the molecular foundations and genetic defenses for enabling long-term human space travel
Epigenetic Basis of Gender Differences in Pediatric GBM
CBTN specimen will be used for reduced representation bisulfite sequencing - we will be profiling the transcriptome and epigenome. We will then compare these profiles between boys and girls with pediatric GBM to identify lesions that cause the difference in clinical outcomes of these patients.