Epigenetic Basis of Gender Differences in Pediatric GBM

Email Principal Investigator
Ongoing
Specimen
HGG
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Sheng Li

CBTN Samples Used

10

CBTN Participants

10

CBTN Samples

Backer

Children's Brain Tumor Project

About this

Project

CBTN specimen will be used for reduced representation bisulfite sequencing - we will be profiling the transcriptome and epigenome. We will then compare these profiles between boys and girls with pediatric GBM to identify lesions that cause the difference in clinical outcomes of these patients.

Ask The

Scientists

Ask the scientists

What are the goals of this project?

The primary aims of this project are to profile the transcriptome and epigenome and compare between boys and girls.

What is the impact of this project?

This project will aims to identify lesions that cause the difference in clinical outcomes of patients with pediatric GBM.

Why the CBTN request is important to this project?

The Children's Brain Tumor Network provides a unique resource of samples to expand our initial cohort.

Specimen Data

The Children's Brain Tumor Network contributed to this project by providing DNA samples.