Senior Director of the Genetic Perturbation Platform and the Functional Genomics Consortium; Institute Scientist
Broad Institute of MIT and Harvard
Dr. David Root is the Senior Director of the Genetic Perturbation Platform and Functional Genomics Consortium at the Broad Institute of MIT and Harvard. He received his PhD in physical chemistry from Stanford University. He was previously assistant professor of physical chemistry at Swarthmore College, then shifted to biological research with postdoctoral work in Brent Stockwell's laboratory at the Whitehead Institute. He has since, launched the Genetic Perturbation Platform and Functional Genomics Consortium at the Broad in 2004 and created some of the world's most-used libraries and tools for RNA interference, gene expression, and CRISPR-based screens, and have pioneered methods to employ these and other tools for functional genomics.
Analysis of Chromatin Pathways as Regulators of High Grade Glioma Gene Expression Patterns
Comprehensive research into high grade gliomas is necessary to find new effective therapies. Using the Pediatric Brain Tumor Atlas, researchers will identify patterns in gene expression that could pave the way for the development of new therapeutics.