Assistant Professor; Director, PNIO Laboratory
University of Pittsburgh
Gary Kohanbash, PhD, joined the faculty of the Department of Neurological Surgery at UPMC Children’s Hospital of Pittsburgh in January of 2017.
Dr. Kohanbash graduated from the University of Pittsburgh in 2007 with a bachelor of science honors degree in neuroscience, specializing in neurodegenerative diseases. He then earned his masters of science degree in infectious diseases and microbiology in 2009, and a doctorate in philosophy in 2012, both from the University of Pittsburgh Graduate School of Public Health. While there, he identified novel pathways of immunosuppression in gliomas and participated in multiple phase I/II immunotherapy clinical trials.
Dr. Kohanbash subsequently completed a post-doctoral fellowship in the University of Pittsburgh Department of Neurological Surgery in 2014. He continued his training as a postdoctoral fellow at the University of California, San Francisco (UCSF) Department of Neurological Surgery. While at UCSF, Dr. Kohanbash was privileged to complete a prestigious T32 training program in translational brain tumor research.
Specialized Areas of Interest: Immunotherapy; theranostics; immunoPET; biomarkers; adoptive cellular therapy; peptide vaccine immunotherapy.
Landscape of tumor-infiltrating T cell repertoire of pediatric brain tumors
Cellular immunity mediated by T-cells is responsible for the detection and neutralization of pathogenic threats. T-cell receptors (TCRs) are highly specialized extracellular receptors that are essential to T-cell specificity and can characterize the T-cell immune status in patients, and normal in