Holly Beale

The Treehouse Childhood Cancer Initiative research focuses on the value of tumor gene expression analysis using RNA sequencing for detecting aberrations in the genome and epigenome. The main objective of this project is to identify therapeutically actionable oncogenes with outlier expression in a

Major advances have been achieved in the discovery and application of targeted therapy for adult solid tumors. Nevertheless, therapeutic options for pediatric solid tumors have been limited. Current precision medicine programs focus on genomic sequencing to identify discrete mutations that may pr