CBTN Executive Director; Director of Operations and Strategic Planning
Center for Data Driven Discovery in Biomedicine
Jena Lilly is the Director of Operations and Strategic Planning for the Center for Data Driven Discovery in Biomedicine. Currently, she leads a team of over 30 people in support of international pediatric oncology research consortiums which combined, include over 25 pediatric hospitals. She is also responsible for the overall operations, strategy and innovation planning and execution for the D3b Center.
Prior to joining CHOP in June of 2008, Jena worked in a developmental biology lab at ASU as well as the nucleic acid facility at Thomas Jefferson University. She also worked for Merck & Co., Inc. as a clinical researcher.
Jena earned a BS in Biology from Arizona State University in Tempe, AZ before completing an MS in Project Management from Drexel University in Philadelphia, PA. She has also earned a certificate from The Leadership Edge Program at The Wharton School of the University of Pennsylvania. Jena is committed to finding new treatments and cures for children with cancer and rare diseases.
Children’s Hospital of Philadelphia
Whole Genome Sequencing and RNA Sequencing of the CBTN Bank for the Pediatric Brain Tumor Atlas
Research into adult cancer has benefited greatly from large scale genomic research. Until now due to the limited resources and availability pediatric brain tumors have not been part of large-scale genomic generation efforts. The CBTN aims to create a comprehensive genomic atlas for use by researchers worldwide to unlock how brain tumors develop, grow, survive, and how they can be treated and cured.
Craniopharyngioma, Medulloblastoma, HGG, (AT/RT), LGG, Ependymoma, Ganglioglioma, DNET, Choroid Plexus Tumors, Meningioma, DIPG, Oligodendroglioma, Schwannoma, Germinoma, Choroid Plexus Tumors, Subependymal Giant cell Astrocytoma, NGGCTs
Proteogenomic and Metabolomic Characterization of Human Glioblastoma
Utilizing genomic data provided by CBTN, researchers deepen their molecular understanding of GBM which could lead to more effective treatments for glioblastoma patients.
Liang-BoWang, Alla Karpova, Marina A. Gritsenko, Jennifer E. Kyle, Song Cao, Yize Li, DmitryRykunov, Antonio Colaprico, Joseph H. Rothstein, Runyu Hong, Vasileios Stathias, MacIntoshCornwell, Francesca Petralia, Yige Wu, Boris Reva, Karsten Krug, Pietro Pugliese, Emily Kawaler, Lindsey K.Olsen, Wen-Wei Liang, Xiaoyu Song, Yongchao Dou, Michael C. Wendl, Wagma Caravan, Wenke Liu, Daniel Cui Zhou, Jiayi Ji, Chia-Feng Tsai, Vladislav A. Petyuk, Jamie Moon, Weiping Ma, Rosalie K. Chu, Karl K. Weitz, Ronald J.Moore, Matthew E. Monroe, Rui Zhao, Xiaolu Yang, Seungyeul Yoo, Azra Krek, Alexis Demopoulos, Houxiang Zhu, Matthew A. Wyczalkowski, Joshua F. McMichael, Brittany L. Henderson, Caleb M. Lindgren, Hannah Boekweg, Shuangjia Lu, Jessika Baral, Lijun Yao, Kelly G. Stratton, Lisa M. Bramer, Erika Zink, Sneha P. Couvillion, Kent J. Bloodsworth, Shankha Satpathy, Weiva Sieh, Simina M. Boca, Stephan Schürer, Feng Chen, Maciej Wiznerowicz, Karen A. Ketchum, Emily S. Boja, Christopher R. Kinsinger, Ana I. Robles, Tara Hiltke, Mathangi Thiagarajan, Alexey I. Nesvizhskii, Bing Zhang, D. R. Mani, Michele Ceccarelli, Xi S. Chen, Sandra L.Cottingham34Qing KayLi35Albert H.Kim36DavidFenyö, Kelly V. Ruggles, Henry Rodriguez, Mehdi Mesri, Samuel H. Payne, Adam C. Resnick, Pei Wang, Richard D. Smith, Antonio Iavarone, Milan G. Chheda, Jill S. Barnholtz-Sloan, Karin D. Rodland, Tao Liu, Li Ding, Clinical Proteomic Tumor Analysis Consortium Anupriya Agarwal, Mitual Amin, Eunkyung An, Matthew L.Anderson, David W.Andrews, Thomas Bauer, Chet Birger, Michael J.Birrer, Lili Blumenberg, William E.Bocik, Uma Borate, Melissa Borucki, Meghan C.Burke, Shuang Cai, Anna P.Calinawan, Steven A.Carr, Sandra Cerda, Daniel W.Chan, Alyssa Charamut, Lin S.Chen, David Chesla, Arul M.Chinnaiyan, ShrabantiChowdhury, Marcin P.Cieślik, David J.Clark, HoustonCulpepper, TomaszCzernicki, FulvioD'Angelo, JacobDay, Stephanie De Young, EmekDemir, Saravana Mohan, Dhanasekaran, Rajiv Dhir, Marcin J.Domagalski, BrianDruker, ElizabethDuffy, MaureenDyer, Nathan J.Edwards, RobertEdwards, KimberlyElburn, Matthew J.Ellis, JenniferEschbacher, AliciaFrancis, Stacey Gabriel, Nikolay Gabrovski, Luciano Garofano, Gad Getz, Michael A.Gillette, Andrew K.Godwin, Denis Golbin, Ziad Hanhan, Linda I.Hannick, Pushpa Hariharan, Barbara Hindenach, Katherine A.Hoadley, Galen Hostetter, Chen Huang, Eric Jaehnig, Scott D.Jewell, Nan Ji, Corbin D.Jones, Alcida Karz, Wojciech Kaspera, Lyndon Kim, Ramani B.Kothadia, Chandan Kumar-Sinha, Jonathan Lei, Felipe D.Leprevost, KaiLi, Yuxing Liao, Jena Lilly, Hongwei Liu, Jan Lubínski, Rashna Madan, William Maggio, Ewa Malc, Anna Malovannaya, Sailaja Mareedu, Sanford P.Markey, AnnetteMarrero-Oliveras, NinaMartinez, Nicollette Maunganidze, Jason E.McDermott, Peter B.McGarvey, John McGee, Piotr Mieczkowski, Simona Migliozzi, Francesmary Modugno, Rebecca Montgomery, Chelsea J.Newton, Gilbert S.Omenn, UmutOzbek, Oxana V.Paklina, Amanda G.Paulovich, Amy M.Perou, Alexander R.Pico, Paul D.Piehowski, Dimitris G.Placantonakis, LarisaPolonskaya, Olga Potapova, BarbaraPruetz, Liqun Qi, Shakti Ramkissoon, Adam Resnick, Shannon Richey, Gregory Riggins, Karna Robinson, Nancy Roche, Daniel C.Rohrer, Brian R.Rood, Larissa Rossell, Sara R.Savage, Eric E.Schadt, Yan Shi, Zhiao Shi, Yvonne Shutack, Shilpi Singh, Tara Skelly, Lori J.Sokoll, Jakub Stawicki, Stephen E.Stein, James Suh, Wojciech Szopa, Dave Tabor, Donghui Tan, Darlene Tansil, Ratna R.Thangudu, Cristina Tognon, Elie Traer, Shirley Tsang, Jeffrey Tyner, Ki SungUm, Dana R.Valley, Suhas Vasaikar, Negin Vatanian, Uma Velvulou, Michael Vernon, Weiqing Wan, Junmei Wang, Alex Webster, Bo Wen, Jeffrey R.Whiteaker, George D.Wilson, Yuriy Zakhartsev, Robert Zelt, Hui Zhang, Liwei Zhang, Zhen Zhang, Grace Zhao, Jun Zhu
Telomere Length Analysis of CNS Tumors in the Pediatric Brain Tumor Atlas
Subsets of pediatric cancers, including high grade glioma (pHGG), have high rates of uniquely long telomeres, associated with ATRX gene mutations and alternative lengthening of telomeres (ALT). Ultimately, these cancers may benefit from a therapy stratification approach. In order to identify and fur
Rokita JL, Gaonkar K, Ijaz H, Miller D, Karras T, Santi M, Martinez D, Koptyra M, De Raedt T, Mason J, Appert E, Lilly J, Zhu Y, Waanders A, Resnick A, Storm J, Cole K.
Children's Brain Tumor Network - Accelerating Research Through Collaboration and Open Science
This presentation highlights the impact and importance of the collaborative and open source nature of CBTN databases and samples.
Jena Lilly, Jennifer Mason, Elizabeth Appert, Allison Heath, Yuankun Zhu, Bo Zhang, Mateusz Koptyra, Mariarita Santi, Ian Pollack, Stewart Goldman, Sarah Leary, Anna Buccoliero, Mirko Scagnet, David Haussler, Derek Hanson, Jiangguo Zhang, Weiqing Wan, Chunde Li, Ron Firestein, Jason Cain, Joanna Phillips, Nalin Gupta, Sabine Mueller, Gerald Grant, Michelle Monje-Deisseroth, Sonia Partap, Jeffrey Greenfield, Brian Rood, Javad Nazarian, Eric Raabe, Eric Jackson, Stacie Stapleton, Robert Lober, David Kram, Phillip Storm, Rishi Lulla, Michael Prados, Adam Resnick, and Angela Waanders
Pediatric High Grade Glioma Resources From the Children’s Brain Tumor Tissue Consortium (CBTTC) and Pediatric Brain Tumor Atlas (PBTA)
In an effort to increase access to high quality pediatric brain tumor samples, researchers describe samples and data prepared and provided through CBTN.
Heba Ijaz, Mateusz Koptyra, Krutika S. Gaonkar, Jo Lynne Rokita, Valerie P. Baubet, Lamiya Tauhid, Yankun Zhu, Miguel Brown, Gonzalo Lopez, Bo Zhang, Sharon J. Diskin, View ORCID ProfileZalman Vaksman, Children’s Brain Tumor Tissue Consortium, Jennifer L. Mason, Elizabeth Appert, Jena Lilly, Rishi Lulla, Thomas De Raedt, Allison P. Heath, Alex Felmeister, Pichai Raman, Javad Nazarian, Maria Rita Santi, Phillip B. Storm, Adam Resnick, Angela J. Waanders, Kristina A. Cole
The Children's Brain Tumor Tissue Consortium (CBTTC) Infrastructure Facilitates Collaborative Research in Pediatric Central Nervous System Tumors
The study and treatment of pediatric brain cancers requires extensive and accessible resources for researchers. This paper describes how CBTN’s database provides such access and supports research.
Alex Felmeister, Rishi Lulla, Angela Waanders, Pichai Raman, Mariarita Santi, Jena Lilly, Jennifer Mason, Javad Nazarian, Adam Resnick