Yale School of Medicine
Dr. Aboian's background training and clinical experience is focused on neuroimaging of primary brain tumors and metastatic cancer to the brain with dedicated subspecialty training in neuroradiology and nuclear medicine. The focus of my research is to identify imaging biomarkers that predict tumor type, tumor molecular signature, and patient outcomes in adult and pediatric brain tumors. To achieve this, I use multimodal approach to study brain cancer, including MRI, radiomics, molecular imaging with positron emission tomography (PET), and hybrid PET/MRI.
Precision Imaging of Pediatric High-grade Gliomas with Quantitative Diffusion Weighted Imaging and Texture Analysis to Identify Imaging Biomarkers That Predict Tumor Genetics and Patient Outcomes
The recently characterized molecular marker, histone H3 K27M, could prove important to the treatment of pediatric gliomas. Researchers will interrogate data from the Pediatric Brain Tumor Atlas in order to better understand this new class of malignant gliomas.