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Cincinnati, Ohio
Cincinnati Children's Hospital Medical Center
research
Medulloblastomas comprises the vast majority of pediatric embryonal tumors and by definition arise in the posterior fossa, where they constitute approximately 40% of all posterior fossa tumors. Other forms of embryonal tumors each make up 2% or less of all childhood brain tumors.The clinical feature
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Frontiers in Cell and Developmental Biology
Through integration of CBTN transcriptomic data (data related to how cells copy DNA to RNA) with additional datasets, researchers identify transcriptional regulator ZNF124 as a cancer driver in medulloblastomas and shine light on new avenues for therapeutic advancement.
Zaili Luo, Xinran Dong, Jianzhong Yu, Yong Xia, Kalen P. Berry, Rohit Rao, Lingli Xu, Ping Xue, Tong Chen, Yifeng Lin, Jiyang Yu, Guoying Huang, Hao Li, Wenhao Zhou, and Q. Richard Lu3
