Medulloblastoma

Medulloblastoma

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443

enrolled participants

name
18
Data Projects Supported
name
18
Specimen Projects Supported
Explore Projects

Summary of

Medulloblastoma

Medulloblastomas comprise the vast majority of pediatric embryonal tumors and by definition arise in the posterior fossa, where they constitute approximately 40% of all posterior fossa tumors. Other forms of embryonal tumors each make up 2% or less of all childhood brain tumors.

The clinical features of childhood embryonal tumors depend on the location of the tumor and the age of the child at the time of presentation. Embryonal tumors tend to be fast-growing tumors and are usually diagnosed within 3 months of the initial onset of symptoms.

(Source: National Cancer Institute)

available Medulloblastoma

Resources

How many participants are enrolled?

443Participants Enrolled

Available CBTN Biospecimens

participants with flash-frozen tissue available405

participants with flash-frozen tissue available

participants with match blood202

participants with match blood

participants with match parental specimens19

participants with match parental specimens

participants with cerebral spinal fluid32

participants with cerebral spinal fluid

Available CBTN Pre-clinical Models

genomically characterized cell lines with data available7

genomically characterized cell lines with data available

genomically characterized pdx with data available2

genomically characterized pdx with data available

Projects supported by the CBTN

Data projects supported0

Data projects supported

Specimen projects supported18

Specimen projects supported

Explore the data in these informatics portals

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How do I get access to the specimens?

To request any of the biospecimens, or pre-clinical model please fill out this form.
Request take approx. 3 months and will require review by the scientific committee and MTA.
Need help? Contact us at research@cbtn.org

How do I get access to the data?

To access the data please follow these instructions. Need help? Contact us at research@cbtn.org
You can access processed data today here by simply logging in to PedcBioPortal
You can request raw data by completing this form. The review normally takes 1 week. Once approved you can access the raw data by creating cohorts of interest on the Kids First Data Resource Portal and performing analysis on the cloud in Cavatica

Flash frozen tissue is tissue from a surgical procedure where the tissue is frozen instantly in liquid nitrogen to ensure there is no degradation

Tissue in freezing media is tissue from a surgical procedure where the tissue is frozen 1 degree at a time over a 24-hour period to keep the tissue intact and compatible with regrowing the tumor for testing

Matched blood is blood that is collected from the patient in addition to tissue from the tumor. This blood provides researchers a direct comparison between normal and tumor specimens for this specific patient

Cerebral Spinal Fluid (CFS) is fluid taken from the the nervous system that researchers can use to study brain tumors

Paternal and maternal specimens are specimens taken from the biological parents of the subject. These specimens provide researchers with the ability to compare tumor and normal tissue and predispositions