Zalman Vaksman

Information regarding the mutations of genes in pediatric brain tumors is integral in developing new diagnostics and treatments. Researchers will use the Pediatric Brain Tumor Atlas to analyze comprehensive genetic information across pediatric brain tumor types, which will be used by researchers in the development of new treatments.

Many pediatric brain cancer patients experience toxicities related to the use of vincristine in treatment protocols. Using the Pediatric Brain Tumor Atlas, this study will help to define the frequency of genetic risks for side effects in an effort to lessen the need for treatment reductions.