Defining the Mutational Landscape of Pediatric Brain Tumors

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Ongoing
Data
All Brain Tumor Types

About this

Project

Understanding the mutational landscape of pediatric brain cancers, gene mutations and their significance in the growth of tumors, is pivotal in developing new treatments. Researchers seek to identify tissue specific changes and pleiotropic alterations, or multiple effects that can arise from a single gene, across pediatric brain tumor types. Such information will be important in the ongoing development of diagnoses, treatments, and assessments. Using the Pediatric Brain Tumor Atlas, researchers will perform initial analysis on Whole Genome Sequencing and RNA sequencing data, comprehensive genetic information that has been gathered across tumor types to complete this work.

Ask The

Scientists

Ask the scientists

What are the goals of this project?

Researchers want to better understand genetic mutations and their effect on the development, growth and persistence of pediatric brain tumors.

What is the impact of this project?

New diagnoses, treatments, and ongoing assessments for many cancer types could be developed with the information gathered in this research.

Why is the CBTN request important to this project?

Comprehensive data across many tumor types is needed to complete this project and the data contained in the Pediatric Brain Tumor Atlas is an invaluable resource.

Specimen Data

The Children's Brain Tumor Network contributed to this project by providing access to the Pediatric Brain Tumor Atlas.

Explore the data in these informatics portals

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