Low-Grade Glioma


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enrolled participants

Data Projects Supported
Specimen Projects Supported
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Summary of

Low-Grade Glioma

Low-Grade Gliomas also called astrocytomas are the most common cancer of the central nervous system in children. They represent a heterogeneous group of tumors that can be discovered anywhere within the brain or spinal cord. Although surgical resection may be curative, up to 20% of children still suffer from the effects of a tumor, which may result in higher rates of morbidity and mortality. The available treatment options for children are limited in recurrent and/or disseminated, or circulated tumors, as well as those with tumors not suited for surgical resection. To date, this significant, un-met need for more effective, targeted therapeutics for children with unresectable or progressive astrocytomas has not yet been satisfied.

Available CBTN Biospecimens

participants with flash-frozen tissue available844

participants with flash-frozen tissue available

participants with match blood469

participants with match blood

participants with match parental specimens71

participants with match parental specimens

participants with cerebral spinal fluid47

participants with cerebral spinal fluid

Available CBTN Pre-clinical Models

genomically characterized cell lines with data available3

genomically characterized cell lines with data available

genomically characterized pdx with data available0

genomically characterized pdx with data available

How do I get access to the specimens?

To request any of the biospecimens, or pre-clinical model please fill out this form.
Request take approx. 3 months and will require review by the scientific committee and MTA.
Need help? Contact us at research@cbtn.org

Explore the data in these informatics portals

How do I get access to the data?

To access the data please follow these instructions. Need help? Contact us at research@cbtn.org
You can access processed data today here by simply logging in to PedcBioPortal
You can request raw data by completing this form. The review normally takes 1 week. Once approved you can access the raw data by creating cohorts of interest on the Kids First Data Resource Portal and performing analysis on the cloud in Cavatica